Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   V5G12_RS09430 Genome accession   NZ_CP145021
Coordinates   1787340..1788593 (-) Length   417 a.a.
NCBI ID   WP_106167122.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_V_2024     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1782340..1793593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G12_RS09395 (V5G12_09410) - 1782354..1782806 (+) 453 Protein_1828 pilin -
  V5G12_RS09400 (V5G12_09415) - 1782772..1783116 (+) 345 Protein_1829 pilin -
  V5G12_RS09405 (V5G12_09425) lpxC 1783951..1784874 (+) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  V5G12_RS09410 (V5G12_09430) - 1785002..1785108 (+) 107 Protein_1831 pilin -
  V5G12_RS09415 (V5G12_09435) pilE 1785411..1785899 (+) 489 WP_171000882.1 pilin Machinery gene
  V5G12_RS09420 (V5G12_09440) - 1786267..1787076 (+) 810 WP_115095436.1 opacity family porin -
  V5G12_RS09425 (V5G12_09445) - 1787050..1787208 (-) 159 WP_154235854.1 hypothetical protein -
  V5G12_RS09430 (V5G12_09450) pilA 1787340..1788593 (-) 1254 WP_106167122.1 signal recognition particle-docking protein FtsY Machinery gene
  V5G12_RS09435 (V5G12_09455) msrAB 1788739..1790307 (+) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  V5G12_RS09440 (V5G12_09460) - 1790391..1790873 (-) 483 WP_003694396.1 CinA family protein -
  V5G12_RS09445 (V5G12_09465) - 1790900..1791748 (-) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  V5G12_RS09450 (V5G12_09470) - 1791842..1792843 (-) 1002 WP_003691948.1 thiamine ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44347.70 Da        Isoelectric Point: 4.8647

>NTDB_id=935996 V5G12_RS09430 WP_106167122.1 1787340..1788593(-) (pilA) [Neisseria gonorrhoeae strain WHO_V_2024]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRGRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLSDTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=935996 V5G12_RS09430 WP_106167122.1 1787340..1788593(-) (pilA) [Neisseria gonorrhoeae strain WHO_V_2024]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGGCCGCGTCAGCCTCAAAGGGCTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCGGGCGATACCTTCCGCGCCGCCGCCCGTGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTCATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATGCCGTCCAAGCCG
CCAAAGCGCGCGGGATCGACATCGTGCTTTCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATTATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)

SRP54-type protein, GTPase domain (SRP54)

(217-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.76

100

0.998