Detailed information
Bioinformatically predicted
Overview
| Name | pilK | Type | Machinery gene |
| Locus tag | V5G14_RS02910 | Genome accession | NZ_CP145017 |
| Coordinates | 564785..565393 (+) | Length | 202 a.a. |
| NCBI ID | WP_047921847.1 | Uniprot ID | A0AA44ZGE4 |
| Organism | Neisseria gonorrhoeae strain WHO_Y_2024 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 565938..604204 | 564785..565393 | flank | 545 |
Gene organization within MGE regions
Location: 564785..604204
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V5G14_RS02910 (V5G14_02915) | pilK | 564785..565393 (+) | 609 | WP_047921847.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| V5G14_RS02915 (V5G14_02920) | pilL | 565395..565868 (+) | 474 | WP_012503482.1 | PilX family type IV pilin | Machinery gene |
| V5G14_RS02920 (V5G14_02925) | - | 565938..566246 (-) | 309 | WP_003706588.1 | AzlD family protein | - |
| V5G14_RS02925 (V5G14_02930) | - | 566243..566954 (-) | 712 | Protein_562 | AzlC family ABC transporter permease | - |
| V5G14_RS02930 (V5G14_02935) | dut | 567120..567572 (+) | 453 | WP_003701071.1 | dUTP diphosphatase | - |
| V5G14_RS02935 (V5G14_02940) | dapC | 567644..568831 (+) | 1188 | WP_003701073.1 | succinyldiaminopimelate transaminase | - |
| V5G14_RS02940 (V5G14_02945) | yaaA | 568987..569766 (+) | 780 | WP_003687925.1 | peroxide stress protein YaaA | - |
| V5G14_RS02955 (V5G14_02960) | - | 570296..571496 (+) | 1201 | Protein_566 | tyrosine-type recombinase/integrase | - |
| V5G14_RS02960 (V5G14_02965) | - | 571852..572121 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| V5G14_RS02965 (V5G14_02970) | - | 572316..572999 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| V5G14_RS02970 (V5G14_02975) | - | 573313..573546 (-) | 234 | Protein_569 | hypothetical protein | - |
| V5G14_RS02975 (V5G14_02980) | - | 573657..573872 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| V5G14_RS02980 (V5G14_02985) | - | 573924..574415 (-) | 492 | WP_047916888.1 | siphovirus Gp157 family protein | - |
| V5G14_RS02985 (V5G14_02990) | - | 574412..574594 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| V5G14_RS02990 (V5G14_02995) | - | 574734..575420 (-) | 687 | WP_042758540.1 | phage replication initiation protein, NGO0469 family | - |
| V5G14_RS02995 (V5G14_03000) | - | 575489..575650 (-) | 162 | WP_003693867.1 | hypothetical protein | - |
| V5G14_RS03000 (V5G14_03005) | - | 575647..575925 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| V5G14_RS03005 (V5G14_03010) | - | 576078..576410 (-) | 333 | WP_003705604.1 | hypothetical protein | - |
| V5G14_RS03010 (V5G14_03015) | - | 576551..576838 (-) | 288 | WP_115154430.1 | hypothetical protein | - |
| V5G14_RS03015 (V5G14_03020) | - | 576835..577311 (-) | 477 | WP_002255718.1 | hypothetical protein | - |
| V5G14_RS03020 (V5G14_03025) | - | 577344..577544 (-) | 201 | WP_047920246.1 | hypothetical protein | - |
| V5G14_RS03025 (V5G14_03030) | - | 578028..578246 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| V5G14_RS03030 (V5G14_03035) | - | 578263..578622 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| V5G14_RS03035 (V5G14_03040) | - | 578623..579162 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| V5G14_RS03040 (V5G14_03045) | - | 579322..580038 (-) | 717 | WP_003695999.1 | helix-turn-helix transcriptional regulator | - |
| V5G14_RS03045 (V5G14_03050) | - | 580419..580646 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| V5G14_RS03050 (V5G14_03055) | - | 580764..581828 (+) | 1065 | WP_050154181.1 | hypothetical protein | - |
| V5G14_RS03055 (V5G14_03060) | - | 581825..583186 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| V5G14_RS03060 (V5G14_03065) | - | 583203..583433 (+) | 231 | WP_012503490.1 | hypothetical protein | - |
| V5G14_RS03065 (V5G14_03070) | - | 583525..584019 (+) | 495 | WP_041421248.1 | DUF3310 domain-containing protein | - |
| V5G14_RS03070 (V5G14_03075) | - | 584196..584345 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| V5G14_RS03075 (V5G14_03080) | - | 584374..584655 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| V5G14_RS03080 (V5G14_03085) | - | 584646..585083 (+) | 438 | WP_047918627.1 | RusA family crossover junction endodeoxyribonuclease | - |
| V5G14_RS03085 (V5G14_03090) | - | 585076..585381 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| V5G14_RS03090 (V5G14_03095) | - | 585378..585761 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| V5G14_RS03095 (V5G14_03100) | - | 585752..586270 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| V5G14_RS03100 (V5G14_03105) | - | 586335..586757 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| V5G14_RS03105 (V5G14_03110) | - | 586757..587296 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| V5G14_RS03110 (V5G14_03115) | - | 587277..588551 (+) | 1275 | WP_003701186.1 | PBSX family phage terminase large subunit | - |
| V5G14_RS03115 (V5G14_03120) | - | 588551..590803 (+) | 2253 | WP_047921418.1 | hypothetical protein | - |
| V5G14_RS03120 (V5G14_03125) | - | 591040..592236 (+) | 1197 | WP_003687992.1 | hypothetical protein | - |
| V5G14_RS03125 (V5G14_03130) | - | 592233..593447 (+) | 1215 | WP_044270986.1 | hypothetical protein | - |
| V5G14_RS03130 (V5G14_03135) | - | 596341..599445 (+) | 3105 | Protein_601 | PLxRFG domain-containing protein | - |
| V5G14_RS03135 (V5G14_03140) | - | 599427..600164 (+) | 738 | WP_003690932.1 | hypothetical protein | - |
| V5G14_RS03140 (V5G14_03145) | - | 600185..601480 (+) | 1296 | WP_003690933.1 | DUF4043 family protein | - |
| V5G14_RS03145 (V5G14_03150) | - | 601535..602008 (+) | 474 | WP_003690936.1 | hypothetical protein | - |
| V5G14_RS03150 (V5G14_03155) | - | 602014..602499 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| V5G14_RS03155 (V5G14_03160) | - | 602496..603170 (+) | 675 | WP_003687998.1 | hypothetical protein | - |
| V5G14_RS03160 (V5G14_03165) | - | 603173..603322 (+) | 150 | WP_003706419.1 | hypothetical protein | - |
| V5G14_RS03165 (V5G14_03170) | - | 603359..604204 (-) | 846 | WP_047921371.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 202 a.a. Molecular weight: 22039.97 Da Isoelectric Point: 7.5810
>NTDB_id=935880 V5G14_RS02910 WP_047921847.1 564785..565393(+) (pilK) [Neisseria gonorrhoeae strain WHO_Y_2024]
MRKQNALTGIPTSEGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNDANEEAFDNIVVKGKPTVEAVKRSCPAKSGKNSTGLCIDNQGVEYKKGTGNVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
MRKQNALTGIPTSEGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNDANEEAFDNIVVKGKPTVEAVKRSCPAKSGKNSTGLCIDNQGVEYKKGTGNVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
Nucleotide
Download Length: 609 bp
>NTDB_id=935880 V5G14_RS02910 WP_047921847.1 564785..565393(+) (pilK) [Neisseria gonorrhoeae strain WHO_Y_2024]
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGAGGGACAGAGGGGGTTCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGATGCTAATGA
AGAGGCTTTTGACAATATCGTGGTGAAAGGCAAGCCCACCGTTGAGGCGGTGAAGCGTTCTTGCCCTGCAAAGTCTGGCA
AAAATTCTACCGGCCTGTGCATTGACAATCAGGGAGTGGAATATAAGAAAGGTACGGGAAACGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGAGGGACAGAGGGGGTTCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGATGCTAATGA
AGAGGCTTTTGACAATATCGTGGTGAAAGGCAAGCCCACCGTTGAGGCGGTGAAGCGTTCTTGCCCTGCAAAGTCTGGCA
AAAATTCTACCGGCCTGTGCATTGACAATCAGGGAGTGGAATATAAGAAAGGTACGGGAAACGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilK | Neisseria gonorrhoeae MS11 |
92.611 |
100 |
0.931 |