Detailed information NTG0935848

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: V5G07_RS08605
• Genome accession: NZ_CP145015
• Coordinates: 1638017..1638466 (-)
• Length: 149 a.a.
• NCBI ID: WP_002214937.1
• Uniprot ID: A0AA44U8B7
• Organism: Neisseria gonorrhoeae strain WHO_Z_2024
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1631463..1645746	1638017..1638466	within	0

Gene organization within MGE regions

Location: 1631463..1645746

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G07_RS08550 (V5G07_08565)	-	1631463..1631741 (-)	279	WP_003691583.1	hypothetical protein	-
V5G07_RS08555 (V5G07_08570)	-	1631748..1631966 (-)	219	WP_003691584.1	major capsid protein	-
V5G07_RS08560 (V5G07_08575)	-	1632040..1632237 (-)	198	WP_003689600.1	hypothetical protein	-
V5G07_RS08565 (V5G07_08580)	-	1632242..1632532 (-)	291	WP_012503914.1	hypothetical protein	-
V5G07_RS08570 (V5G07_08585)	-	1632577..1633925 (-)	1349	Protein_1673	replication initiation factor domain-containing protein	-
V5G07_RS08575 (V5G07_08590)	-	1634064..1634486 (-)	423	WP_003691751.1	very short patch repair endonuclease	-
V5G07_RS08580 (V5G07_08595)	-	1634492..1635088 (-)	597	WP_012503916.1	TIGR02391 family protein	-
V5G07_RS08585 (V5G07_08600)	-	1635278..1636135 (-)	858	WP_012503917.1	ATP-binding protein	-
V5G07_RS08590 (V5G07_08605)	-	1636149..1636478 (-)	330	WP_002234365.1	DNA cytosine methyltransferase	-
V5G07_RS08595 (V5G07_08610)	-	1636517..1637125 (-)	609	WP_080229275.1	DNA cytosine methyltransferase	-
V5G07_RS08600 (V5G07_08615)	-	1637494..1637640 (+)	147	WP_003691757.1	hypothetical protein	-
V5G07_RS08605 (V5G07_08620)	comP	1638017..1638466 (-)	450	WP_002214937.1	type IV pilin protein	Machinery gene
V5G07_RS08610 (V5G07_08625)	comE	1638554..1638949 (-)	396	WP_003703428.1	helix-hairpin-helix domain-containing protein	Machinery gene
V5G07_RS08615 (V5G07_08630)	-	1639051..1639170 (-)	120	Protein_1682	competence protein ComE	-
V5G07_RS08645 (V5G07_08660)	-	1644795..1645448 (-)	654	Protein_1683	TIGR01621 family pseudouridine synthase	-
V5G07_RS08650 (V5G07_08665)	-	1645402..1645746 (-)	345	WP_003691787.1	HAD hydrolase family protein	-

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16834.81 Da
• Isoelectric Point: 9.7951

>NTDB_id=935848 V5G07_RS08605 WP_002214937.1 1638017..1638466(-) (comP) [Neisseria gonorrhoeae strain WHO_Z_2024]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=935848 V5G07_RS08605 WP_002214937.1 1638017..1638466(-) (comP) [Neisseria gonorrhoeae strain WHO_Z_2024]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	100	100	1
comP	Neisseria meningitidis 8013	99.329	100	0.993
comP	Neisseria subflava NJ9703	49.66	98.658	0.49