Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   ACD269_RS00930 Genome accession   NZ_CP168260
Coordinates   172353..172793 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain FC2     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 167353..177793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD269_RS00905 (ACD269_00905) - 167614..168900 (+) 1287 WP_050228975.1 response regulator transcription factor -
  ACD269_RS00910 (ACD269_00910) - 168952..169485 (+) 534 WP_000729029.1 hypothetical protein -
  ACD269_RS00915 (ACD269_00915) nrdI 169563..170033 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  ACD269_RS00920 (ACD269_00920) - 170326..171588 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  ACD269_RS00925 (ACD269_00925) - 171898..172356 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  ACD269_RS00930 (ACD269_00930) brsR 172353..172793 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  ACD269_RS00935 (ACD269_00935) - 172881..173006 (-) 126 WP_001822433.1 hypothetical protein -
  ACD269_RS00940 (ACD269_00940) hexB 173149..175098 (+) 1950 WP_000018154.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACD269_RS00945 (ACD269_00945) ribE 175423..175890 (-) 468 WP_001099505.1 6,7-dimethyl-8-ribityllumazine synthase -
  ACD269_RS00950 (ACD269_00950) - 175891..177096 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  ACD269_RS00955 (ACD269_00955) ribE 177116..177751 (-) 636 WP_016398423.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=935183 ACD269_RS00930 WP_000861956.1 172353..172793(-) (brsR) [Streptococcus pneumoniae strain FC2]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=935183 ACD269_RS00930 WP_000861956.1 172353..172793(-) (brsR) [Streptococcus pneumoniae strain FC2]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363