Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   V3435_RS11430 Genome accession   NZ_CP144270
Coordinates   2315055..2316692 (-) Length   545 a.a.
NCBI ID   WP_031912755.1    Uniprot ID   -
Organism   Staphylococcus aureus strain LA52     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2308290..2323670 2315055..2316692 within 0


Gene organization within MGE regions


Location: 2308290..2323670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3435_RS11395 (V3435_11390) mecA 2308290..2310299 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  V3435_RS11400 (V3435_11395) - 2310396..2311382 (+) 987 WP_350950092.1 M56 family metallopeptidase -
  V3435_RS11405 (V3435_11400) - 2311354..2311614 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  V3435_RS11410 (V3435_11405) - 2311605..2313212 (-) 1608 Protein_2191 IS1182 family transposase -
  V3435_RS11415 (V3435_11410) - 2313264..2313770 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  V3435_RS11420 (V3435_11415) - 2313785..2314096 (-) 312 WP_000700851.1 DUF960 family protein -
  V3435_RS11425 (V3435_11420) - 2314183..2314533 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  V3435_RS11430 (V3435_11425) ccrB 2315055..2316692 (-) 1638 WP_031912755.1 recombinase family protein Machinery gene
  V3435_RS11435 (V3435_11430) ccrA 2316714..2318063 (-) 1350 WP_000815652.1 recombinase family protein Machinery gene
  V3435_RS11440 (V3435_11435) - 2318297..2320084 (-) 1788 WP_000122621.1 DUF927 domain-containing protein -
  V3435_RS11445 (V3435_11440) - 2320084..2320374 (-) 291 WP_001036437.1 hypothetical protein -
  V3435_RS11450 (V3435_11445) - 2320513..2321562 (+) 1050 WP_000613248.1 hypothetical protein -
  V3435_RS11455 (V3435_11450) - 2322180..2323670 (+) 1491 WP_000554504.1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 545 a.a.        Molecular weight: 62967.16 Da        Isoelectric Point: 9.9805

>NTDB_id=933132 V3435_RS11430 WP_031912755.1 2315055..2316692(-) (ccrB) [Staphylococcus aureus strain LA52]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
IYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTTNT
LKDGTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVARVNQENKVDGAALHHDIAYKQQ
QYDEVQTKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKSLFDAKQISKLLQHIFQDIKHMEKS
RLKALYLSVIDRINIRKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1638 bp        

>NTDB_id=933132 V3435_RS11430 WP_031912755.1 2315055..2316692(-) (ccrB) [Staphylococcus aureus strain LA52]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATAGATTGTGTTATG
ATCTACAAAACAAACCGATTAGCTCGTAATACATCGGATCTTCTGAAAATCGTCGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGGCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTCCTATGCCAAAGGACATGGCTATCGTAAAATAGCCAATGCATTGAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTTCATGGTAAAGGAACGA
ATCTGCTTACAGGCATTATCCATTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACAACGAATACA
CTTAAAGATGGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGC
AAACAGTGTAAGAGCTGATGTGATTGAAGATTATGTAATGAAGCAAATACTCGAAATAGTCAAAAGTGATAAAGTCATTC
AACGCGTTGTAGCACGTGTTAATCAAGAAAATAAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAA
CAATATGATGAAGTACAAACCAAACTAAATAACTTGATTAAAACCATAGAGGATAATCCGGACTTAACATCAGTAATCAG
ACCAAGTATTCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAG
ATAAGTCTTTATTTGATGCCAAACAAATCAGTAAACTATTACAACACATCTTTCAAGATATTAAGCACATGGAAAAATCT
CGACTCAAAGCATTGTACCTATCAGTGATTGATCGTATTAATATTAGAAAAGATGGTAATCATAAAAAACAATTCTATGT
CACACTCAAACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGT
CTTTATTTTTGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-359)

Recombinase (Recombinase)

(180-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

96.881

100

0.969