Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   V3435_RS07630 Genome accession   NZ_CP144270
Coordinates   1541509..1542225 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain LA52     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1536509..1547225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3435_RS07600 (V3435_07595) - 1536776..1537402 (+) 627 WP_000522384.1 nitroreductase family protein -
  V3435_RS07605 (V3435_07600) - 1537710..1538495 (+) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  V3435_RS07610 (V3435_07605) - 1539097..1539231 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  V3435_RS07615 (V3435_07610) agrB 1539467..1540036 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  V3435_RS07620 (V3435_07615) agrD 1540033..1540173 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  V3435_RS07625 (V3435_07620) agrC 1540198..1541490 (+) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  V3435_RS07630 (V3435_07625) agrA 1541509..1542225 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  V3435_RS07635 (V3435_07630) - 1542599..1543558 (-) 960 WP_001253294.1 carbohydrate kinase -
  V3435_RS07640 (V3435_07635) - 1543555..1545039 (-) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  V3435_RS07645 (V3435_07640) - 1545188..1546138 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=933124 V3435_RS07630 WP_000688492.1 1541509..1542225(+) (agrA) [Staphylococcus aureus strain LA52]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=933124 V3435_RS07630 WP_000688492.1 1541509..1542225(+) (agrA) [Staphylococcus aureus strain LA52]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1