Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   V2K10_RS07625 Genome accession   NZ_CP167067
Coordinates   1505297..1508125 (-) Length   942 a.a.
NCBI ID   WP_021340890.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 21     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1500297..1513125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V2K10_RS07595 (V2K10_007595) - 1500973..1501938 (+) 966 WP_002988504.1 LacI family DNA-binding transcriptional regulator -
  V2K10_RS07600 (V2K10_007600) nusB 1502079..1502531 (-) 453 WP_002988501.1 transcription antitermination factor NusB -
  V2K10_RS07605 (V2K10_007605) - 1502524..1502913 (-) 390 WP_002983163.1 Asp23/Gls24 family envelope stress response protein -
  V2K10_RS07610 (V2K10_007610) efp 1502959..1503516 (-) 558 WP_002988496.1 elongation factor P -
  V2K10_RS07615 (V2K10_007615) - 1503612..1504073 (-) 462 WP_002988493.1 deaminase -
  V2K10_RS07620 (V2K10_007620) - 1504108..1505181 (-) 1074 WP_002988490.1 Xaa-Pro peptidase family protein -
  V2K10_RS07625 (V2K10_007625) uvrA 1505297..1508125 (-) 2829 WP_021340890.1 excinuclease ABC subunit UvrA Machinery gene
  V2K10_RS07630 (V2K10_007630) - 1508328..1509272 (+) 945 WP_002983147.1 magnesium transporter CorA family protein -
  V2K10_RS07635 (V2K10_007635) - 1509404..1510060 (+) 657 WP_002983144.1 DUF1129 domain-containing protein -
  V2K10_RS07640 (V2K10_007640) rpsR 1510193..1510432 (-) 240 WP_002983142.1 30S ribosomal protein S18 -
  V2K10_RS07645 (V2K10_007645) ssb 1510597..1511088 (-) 492 WP_002983122.1 single-stranded DNA-binding protein Machinery gene
  V2K10_RS07650 (V2K10_007650) rpsF 1511110..1511400 (-) 291 WP_002983117.1 30S ribosomal protein S6 -
  V2K10_RS07655 (V2K10_007655) - 1511573..1511866 (-) 294 WP_002983113.1 hypothetical protein -

Sequence

Protein


Download         Length: 942 a.a.        Molecular weight: 104062.23 Da        Isoelectric Point: 6.0690

>NTDB_id=931981 V2K10_RS07625 WP_021340890.1 1505297..1508125(-) (uvrA) [Streptococcus pyogenes strain Isolate 21]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVIYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide


Download         Length: 2829 bp        

>NTDB_id=931981 V2K10_RS07625 WP_021340890.1 1505297..1508125(-) (uvrA) [Streptococcus pyogenes strain Isolate 21]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTCGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTTACGGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGTTATGTCCGTGTGCGGGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCCAAAAGTAAGATGCACAACATCGAGGTGGTTATTGACCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGGTTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAGAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGAGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGATATTCCTTTTG
AAGGTGTTGTGACTAATGTTAATCGTCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAATTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTGTCACGGGCTGCTGGGACTTTATCAGGTGGTGAAAGTCAACGAATCAGGTTAGCGACACAAATTGGTTCTAACTT
ATCAGGGGTGATCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGGCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTACTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGTAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCCACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(624-860)

UvrA interaction domain (UvrA_inter)

(132-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

84.82

100

0.848
  uvrA Streptococcus pneumoniae TIGR4

84.82

100

0.848
  uvrA Streptococcus pneumoniae D39

84.82

100

0.848