Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   ACB345_RS06270 Genome accession   NZ_CP167025
Coordinates   1268356..1270341 (-) Length   661 a.a.
NCBI ID   WP_031488488.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1263356..1275341
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB345_RS06245 (ACB345_06245) - 1263367..1264617 (-) 1251 WP_031488492.1 glutamate-5-semialdehyde dehydrogenase -
  ACB345_RS06250 (ACB345_06250) proB 1264610..1265431 (-) 822 WP_031488491.1 glutamate 5-kinase -
  ACB345_RS06255 (ACB345_06255) - 1265496..1267124 (-) 1629 WP_031488490.1 ABC transporter permease -
  ACB345_RS06260 (ACB345_06260) - 1267129..1267863 (-) 735 WP_002988881.1 ABC transporter ATP-binding protein -
  ACB345_RS06265 (ACB345_06265) - 1267897..1268163 (-) 267 WP_031488489.1 bacteriocin immunity protein -
  ACB345_RS06270 (ACB345_06270) recP/tkt 1268356..1270341 (-) 1986 WP_031488488.1 transketolase Machinery gene
  ACB345_RS06275 (ACB345_06275) fsa 1270559..1271203 (-) 645 WP_031488487.1 fructose-6-phosphate aldolase -
  ACB345_RS06280 (ACB345_06280) - 1271329..1272828 (-) 1500 WP_031488486.1 helix-turn-helix domain-containing protein -
  ACB345_RS06285 (ACB345_06285) - 1272818..1274164 (-) 1347 WP_031488485.1 FAD/NAD(P)-binding oxidoreductase -
  ACB345_RS06290 (ACB345_06290) - 1274273..1274974 (-) 702 WP_031488484.1 MIP/aquaporin family protein -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 71422.15 Da        Isoelectric Point: 4.5976

>NTDB_id=931883 ACB345_RS06270 WP_031488488.1 1268356..1270341(-) (recP/tkt) [Streptococcus pyogenes strain Isolate]
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYE
AEYPELAAEYQKAFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEV
KLAMDTQEALEAEDIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=931883 ACB345_RS06270 WP_031488488.1 1268356..1270341(-) (recP/tkt) [Streptococcus pyogenes strain Isolate]
ATGACATTTGATGCAATTGACCAATTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC
TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA
CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTGCAT
TTAGCAGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGT
GAACCACACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAG
AAGCTCACCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGT
GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA
TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTACGGTT
GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG
AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC
TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAA
CAGAGCGCTTTGCTCAAGGTCTTCAAGCGCGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATGAA
GCAGAATATCCAGAATTAGCAGCAGAATACCAAAAAGCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGA
ACTTGGTAGTTCAATGGCGAGTCGTGTATCCAGTCAGCAAGCTATCCAACAAATTTCAGAACAAGTAGCCTCTTTCTGGG
GTGGGTCAGCAGACCTTTCAGCTTCAAACAATACTATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGC
CGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGT
TTACGGCGGAACCTTCTTTGTCTTCTCAAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAG
TTTATGTCATGACACATGATTCTATCGCTGTCGGTGAAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT
CGCTCAATGCCTAACTTGAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA
AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAACCTTCCAGTGCTTGAGGGCACAAAAGAATTGGCAGAAGATG
GTCTTAACAAAGGAGCTTATATCTTGTCAGAAGCCAAAGGCGACCTTGATGGTATCATCATTGCAACAGGTTCAGAAGTG
AAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCAGAAGACATTCATGTGCGTGTCGTATCTATGCCATCACAAAATAT
CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT
CAAGCTTTGGCTGGGCAAAATATGTCGGCCTAGCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA
AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAG

Domains

Predicted by InterProScan.

Transketolase, C-terminal domain (Transketolase_C)

(552-652)

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(6-335)

Transketolase, pyrimidine binding domain (Transket_pyr)

(352-522)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

55.471

99.546

0.552