Detailed information NTG0931812

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ACB338_RS08935
• Genome accession: NZ_CP167024
• Coordinates: 1772614..1773381 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1767614..1778381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB338_RS08920 (ACB338_08925)	hexB	1768132..1770114 (-)	1983	WP_010922757.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACB338_RS08925 (ACB338_08930)	-	1770209..1771360 (-)	1152	WP_003058754.1	site-specific integrase	-
ACB338_RS08930 (ACB338_08935)	-	1771609..1771752 (+)	144	WP_011185066.1	putative holin-like toxin	-
ACB338_RS08935 (ACB338_08940)	irvR	1772614..1773381 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
ACB338_RS08940 (ACB338_08945)	-	1773535..1773741 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
ACB338_RS08945 (ACB338_08950)	-	1773775..1773975 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
ACB338_RS08950 (ACB338_08955)	-	1773996..1774403 (+)	408	WP_002992501.1	hypothetical protein	-
ACB338_RS08955 (ACB338_08960)	-	1774416..1774538 (+)	123	WP_011285272.1	hypothetical protein	-
ACB338_RS08960 (ACB338_08965)	-	1774821..1775342 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
ACB338_RS08965 (ACB338_08970)	-	1775590..1775763 (+)	174	WP_000132665.1	hypothetical protein	-
ACB338_RS08970 (ACB338_08975)	-	1775925..1776356 (+)	432	WP_136302445.1	hypothetical protein	-
ACB338_RS08975 (ACB338_08980)	-	1776458..1776790 (+)	333	WP_011285276.1	hypothetical protein	-
ACB338_RS08980 (ACB338_08985)	-	1776790..1776981 (+)	192	WP_021340709.1	hypothetical protein	-
ACB338_RS08985 (ACB338_08990)	-	1776993..1777322 (+)	330	WP_003058810.1	hypothetical protein	-
ACB338_RS08990 (ACB338_08995)	-	1777325..1777597 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=931812 ACB338_RS08935 WP_003058809.1 1772614..1773381(-) (irvR) [Streptococcus pyogenes strain Isolate]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=931812 ACB338_RS08935 WP_003058809.1 1772614..1773381(-) (irvR) [Streptococcus pyogenes strain Isolate]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4