Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ACB335_RS04230 Genome accession   NZ_CP167022
Coordinates   801580..802056 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain Isolate 4     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 796580..807056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB335_RS04205 (ACB335_04205) - 796621..797409 (+) 789 WP_031488333.1 Nif3-like dinuclear metal center hexameric protein -
  ACB335_RS04210 (ACB335_04210) - 797449..798555 (+) 1107 WP_031488332.1 FAD-binding oxidoreductase -
  ACB335_RS04215 (ACB335_04215) rfbA 798613..799482 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  ACB335_RS04220 (ACB335_04220) - 799482..800075 (+) 594 WP_031488331.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  ACB335_RS04225 (ACB335_04225) rfbB 800319..801359 (+) 1041 WP_010922196.1 dTDP-glucose 4,6-dehydratase -
  ACB335_RS04230 (ACB335_04230) mutX 801580..802056 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ACB335_RS04235 (ACB335_04235) - 802114..803295 (+) 1182 WP_031488330.1 AI-2E family transporter -
  ACB335_RS04240 (ACB335_04240) - 803285..804532 (+) 1248 WP_002984878.1 tetratricopeptide repeat protein -
  ACB335_RS04245 (ACB335_04245) fbp54 804591..806243 (-) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=931571 ACB335_RS04230 WP_002984880.1 801580..802056(+) (mutX) [Streptococcus pyogenes strain Isolate 4]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=931571 ACB335_RS04230 WP_002984880.1 801580..802056(+) (mutX) [Streptococcus pyogenes strain Isolate 4]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703