Detailed information NTG0931380

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACB327_RS03475
• Genome accession: NZ_CP167020
• Coordinates: 680279..682378 (-)
• Length: 699 a.a.
• NCBI ID: WP_076639696.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 6
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 675279..687378

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB327_RS03450 (ACB327_03450)	-	675756..676595 (+)	840	WP_129322654.1	thymidylate synthase	-
ACB327_RS03455 (ACB327_03455)	-	676675..677172 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ACB327_RS03460 (ACB327_03460)	clpX	677492..678721 (+)	1230	WP_011888976.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACB327_RS03465 (ACB327_03465)	yihA	678731..679330 (+)	600	WP_076639697.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ACB327_RS03470 (ACB327_03470)	-	679478..680221 (+)	744	WP_371400122.1	hypothetical protein	-
ACB327_RS03475 (ACB327_03475)	clpC	680279..682378 (-)	2100	WP_076639696.1	AAA family ATPase	Regulator
ACB327_RS03480 (ACB327_03480)	rpiA	682756..683439 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-
ACB327_RS03485 (ACB327_03485)	-	683516..684727 (+)	1212	WP_023079502.1	phosphopentomutase	-
ACB327_RS03490 (ACB327_03490)	arsC	684743..685183 (+)	441	WP_076634090.1	arsenate reductase (glutaredoxin)	-
ACB327_RS03495 (ACB327_03495)	-	685167..685976 (+)	810	WP_129322655.1	purine-nucleoside phosphorylase	-
ACB327_RS03500 (ACB327_03500)	deoD	686642..687355 (+)	714	WP_002990147.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77346.41 Da
• Isoelectric Point: 5.5548

>NTDB_id=931380 ACB327_RS03475 WP_076639696.1 680279..682378(-) (clpC) [Streptococcus pyogenes strain Isolate 6]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEACQGHLDPIIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPDVKKLQAILKEGQLVIRQNDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=931380 ACB327_RS03475 WP_076639696.1 680279..682378(-) (clpC) [Streptococcus pyogenes strain Isolate 6]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTTGTCAAGGACATCTTGACCCCATCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCCGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAATATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTCGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTTACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGGCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTCACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGCTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGACGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAACGATCAGTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• AAA lid domain (AAA_lid_9) (259-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.657	100	0.469
clpE	Streptococcus mutans UA159	48.758	92.132	0.449
clpE	Streptococcus pneumoniae TIGR4	49.117	89.127	0.438
clpE	Streptococcus pneumoniae Rx1	49.117	89.127	0.438
clpE	Streptococcus pneumoniae D39	49.117	89.127	0.438
clpE	Streptococcus pneumoniae R6	49.117	89.127	0.438
clpC	Bacillus subtilis subsp. subtilis str. 168	44.511	95.136	0.423
clpC	Streptococcus thermophilus LMG 18311	42.947	91.273	0.392
clpC	Streptococcus thermophilus LMD-9	42.79	91.273	0.391
clpC	Streptococcus pneumoniae Rx1	41.564	93.276	0.388
clpC	Streptococcus pneumoniae D39	41.564	93.276	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.194	93.419	0.385
clpC	Streptococcus pneumoniae TIGR4	42.54	90.129	0.383
clpC	Streptococcus mutans UA159	41.406	91.559	0.379