Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   ACB337_RS06990 Genome accession   NZ_CP167017
Coordinates   1369511..1371496 (-) Length   661 a.a.
NCBI ID   WP_010922560.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 9     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1364511..1376496
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB337_RS06965 (ACB337_06970) - 1364522..1365772 (-) 1251 WP_010922557.1 glutamate-5-semialdehyde dehydrogenase -
  ACB337_RS06970 (ACB337_06975) proB 1365765..1366586 (-) 822 WP_010922558.1 glutamate 5-kinase -
  ACB337_RS06975 (ACB337_06980) - 1366651..1368279 (-) 1629 WP_011285662.1 ABC transporter permease -
  ACB337_RS06980 (ACB337_06985) - 1368284..1369018 (-) 735 WP_002988881.1 ABC transporter ATP-binding protein -
  ACB337_RS06985 (ACB337_06990) - 1369052..1369318 (-) 267 WP_011285663.1 bacteriocin immunity protein -
  ACB337_RS06990 (ACB337_06995) recP/tkt 1369511..1371496 (-) 1986 WP_010922560.1 transketolase Machinery gene
  ACB337_RS06995 (ACB337_07000) fsa 1371714..1372358 (-) 645 WP_002983569.1 fructose-6-phosphate aldolase -
  ACB337_RS07000 (ACB337_07005) - 1372484..1373983 (-) 1500 WP_011285664.1 helix-turn-helix domain-containing protein -
  ACB337_RS07005 (ACB337_07010) - 1373973..1375319 (-) 1347 WP_010922562.1 FAD/NAD(P)-binding oxidoreductase -
  ACB337_RS07010 (ACB337_07015) - 1375428..1376129 (-) 702 WP_011285665.1 MIP/aquaporin family protein -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 71353.09 Da        Isoelectric Point: 4.6233

>NTDB_id=931118 ACB337_RS06990 WP_010922560.1 1369511..1371496(-) (recP/tkt) [Streptococcus pyogenes strain Isolate 9]
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYE
AEYPELAAEYQKAFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLSKGAYILSEAKGDLDGILIATGSEV
KLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLSGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=931118 ACB337_RS06990 WP_010922560.1 1369511..1371496(-) (recP/tkt) [Streptococcus pyogenes strain Isolate 9]
ATGACATTTGATGCAATTGACCAGTTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC
TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA
CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTACAC
TTAGCTGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGT
GAACCACACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGGATGGCCATGGCAG
AAGCTCATCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGT
GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA
TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTATGGTT
GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG
AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC
TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAA
CAGAGCGCTTTGCTCAAGGTCTTCAAGCGCGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATGAA
GCAGAATATCCAGAATTAGCAGCAGAATACCAAAAAGCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGA
ACTTGGTAGTTCAATGGCGAGTCGTGTATCCAGTCAACAAGCCATCCAACAAATTTCAGAACAAGTAGCCTCTTTCTGGG
GTGGGTCAGCAGACCTTTCAGCTTCAAACAATACTATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGC
CGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGT
TTACGGCGGAACCTTCTTTGTCTTCTCAAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAG
TTTATGTCATGACACATGATTCTATCGCTGTCGGTGAAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT
CGCTCAATGCCTAACTTGAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA
AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAACCTTCCAGTGCTTGAGGGCACAAAAGAATTGGCAGAAGATG
GTCTTAGCAAAGGAGCTTATATCTTGTCAGAAGCCAAAGGCGACCTTGATGGTATCTTGATTGCAACAGGTTCAGAAGTG
AAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCAGAAGGCATTCATGTGCGTGTCGTATCTATGCCATCACAAAATAT
CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT
CAAGCTTTGGCTGGGCAAAATATGTCGGCCTATCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA
AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAA

Domains

Predicted by InterProScan.

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(6-335)

Transketolase, pyrimidine binding domain (Transket_pyr)

(352-522)

Transketolase, C-terminal domain (Transketolase_C)

(552-652)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

55.471

99.546

0.552