Detailed information NTG0931034

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: ACB332_RS07050
• Genome accession: NZ_CP167016
• Coordinates: 1420227..1423055 (-)
• Length: 942 a.a.
• NCBI ID: WP_371400094.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 10
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1415227..1428055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB332_RS07020 (ACB332_07020)	-	1415905..1416870 (+)	966	WP_014635676.1	LacI family DNA-binding transcriptional regulator	-
ACB332_RS07025 (ACB332_07025)	nusB	1417011..1417463 (-)	453	WP_021775468.1	transcription antitermination factor NusB	-
ACB332_RS07030 (ACB332_07030)	-	1417456..1417845 (-)	390	WP_002983163.1	Asp23/Gls24 family envelope stress response protein	-
ACB332_RS07035 (ACB332_07035)	efp	1417891..1418448 (-)	558	WP_002988496.1	elongation factor P	-
ACB332_RS07040 (ACB332_07040)	-	1418536..1419003 (-)	468	WP_021775474.1	deaminase	-
ACB332_RS07045 (ACB332_07045)	-	1419038..1420111 (-)	1074	WP_020905443.1	Xaa-Pro peptidase family protein	-
ACB332_RS07050 (ACB332_07050)	uvrA	1420227..1423055 (-)	2829	WP_371400094.1	excinuclease ABC subunit UvrA	Machinery gene
ACB332_RS07055 (ACB332_07055)	-	1423258..1424202 (+)	945	WP_002983147.1	magnesium transporter CorA family protein	-
ACB332_RS07060 (ACB332_07060)	-	1424334..1424990 (+)	657	WP_002983144.1	DUF1129 domain-containing protein	-
ACB332_RS07065 (ACB332_07065)	rpsR	1425123..1425362 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
ACB332_RS07070 (ACB332_07070)	ssb	1425527..1426018 (-)	492	WP_371400063.1	single-stranded DNA-binding protein	Machinery gene
ACB332_RS07075 (ACB332_07075)	rpsF	1426040..1426330 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
ACB332_RS07080 (ACB332_07080)	-	1426503..1426796 (-)	294	WP_002983113.1	hypothetical protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 103938.05 Da
• Isoelectric Point: 6.1359

>NTDB_id=931034 ACB332_RS07050 WP_371400094.1 1420227..1423055(-) (uvrA) [Streptococcus pyogenes strain Isolate 10]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEITASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGITKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKGKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=931034 ACB332_RS07050 WP_371400094.1 1420227..1423055(-) (uvrA) [Streptococcus pyogenes strain Isolate 10]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTTGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTGACTGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCACCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGTTATGTCCGTGTGCGGGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCAAAAAGTAAGATGCACAACATCGAGGTGGTTATTGATCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AACGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGGTTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAAAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGTGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTAACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCTTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAATTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATCCATGACCGTCTGACATTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTGTCACGGGCTGCTGGGACTTTATCAGGTGGTGAAAGTCAACGAATCAGGTTAGCAACACAAATTGGTTCTAACCT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCATCAAAGAGACAATGACCGTTTGATCGAGAGCCTGA
AAAAAATGCGTGATTTGGGTAATACGTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGACCGGGGGCAGGTGAGTTCGGTGGAGAAATTACTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCTTTAGAGCGCCGTTCTGGTAATGGCCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGATTGATTGACATTGACCAAAGTCCGATTG
GAAGGACACCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGTTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGCCGTTGTGAGGCTTGTTCAGGTGATGG
GATTACCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTACAAAGGAAAAAATATCGCAGAAGTCCTTGATATGACTGTGGATGATGCCTTGGTATTTTTC
TCTGCTATTCCTAAAATCGCTCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGCAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCTACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

• ABC transporter (ABC_tran) (624-860)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	84.607	100	0.846
uvrA	Streptococcus pneumoniae TIGR4	84.607	100	0.846
uvrA	Streptococcus pneumoniae D39	84.607	100	0.846