Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   ACB332_RS06470 Genome accession   NZ_CP167016
Coordinates   1296444..1298429 (-) Length   661 a.a.
NCBI ID   WP_030127293.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 10     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1291444..1303429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB332_RS06445 (ACB332_06445) - 1291455..1292705 (-) 1251 WP_129322744.1 glutamate-5-semialdehyde dehydrogenase -
  ACB332_RS06450 (ACB332_06450) proB 1292698..1293519 (-) 822 Protein_1214 glutamate 5-kinase -
  ACB332_RS06455 (ACB332_06455) - 1293584..1295212 (-) 1629 WP_044559859.1 ABC transporter permease -
  ACB332_RS06460 (ACB332_06460) - 1295217..1295951 (-) 735 WP_002988881.1 ABC transporter ATP-binding protein -
  ACB332_RS06465 (ACB332_06465) - 1295985..1296251 (-) 267 WP_002988878.1 bacteriocin immunity protein -
  ACB332_RS06470 (ACB332_06470) recP/tkt 1296444..1298429 (-) 1986 WP_030127293.1 transketolase Machinery gene
  ACB332_RS06475 (ACB332_06475) fsa 1298647..1299291 (-) 645 WP_129322746.1 fructose-6-phosphate aldolase -
  ACB332_RS06480 (ACB332_06480) - 1299417..1300916 (-) 1500 WP_371400060.1 helix-turn-helix domain-containing protein -
  ACB332_RS06485 (ACB332_06485) - 1300906..1302249 (-) 1344 WP_371400061.1 FAD/NAD(P)-binding oxidoreductase -
  ACB332_RS06490 (ACB332_06490) - 1302358..1303059 (-) 702 WP_076639425.1 MIP/aquaporin family protein -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 71362.13 Da        Isoelectric Point: 4.6553

>NTDB_id=931028 ACB332_RS06470 WP_030127293.1 1296444..1298429(-) (recP/tkt) [Streptococcus pyogenes strain Isolate 10]
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYE
AEYPELAAEYQKAFANEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQSLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEV
KLALDTQDKLESEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=931028 ACB332_RS06470 WP_030127293.1 1296444..1298429(-) (recP/tkt) [Streptococcus pyogenes strain Isolate 10]
ATGACATTTGATGCAATTGACCAATTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC
TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA
CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTGCAT
TTAGCAGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGT
GAACCATACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAG
AAGCTCACCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGT
GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA
TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTATGGTT
GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG
AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC
TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAA
CAGAGCGCTTTGCTCAAGGTCTTCAAGCGCGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATGAA
GCAGAATATCCAGAATTAGCAGCAGAATACCAAAAAGCCTTTGCTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGA
ACTTGGTAGCTCAATGGCGAGTCGTGTATCCAGTCAACAAGCCATCCAACAAATTTCAGAACAAGTAGCCTCTTTCTGGG
GTGGGTCAGCAGACCTTTCAGCATCTAACAACACTATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCATTATGAAGGC
CGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGTGGAACACGCGT
TTACGGTGGAACCTTCTTTGTCTTCTCAAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAGCTTACCAACAG
TTTATGTCATGACACATGATTCTATCGCTGTCGGTGAGGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT
CGTTCAATGCCTAACTTGAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA
AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAACCTCCCAGTGCTTGAAGGAACAAAAGAATTGGCAGAAGATG
GTCTTAACAAAGGAGCTTACATCTTGTCAGAAGCCAAAGGCGACCTTGAAGGTATCTTGATTGCAACAGGTTCAGAAGTT
AAATTAGCTTTAGATACTCAAGATAAACTTGAGTCAGAAGGCATTCATGTTCGCGTCGTATCTATGCCATCGCAAAATAT
CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT
CAAGCTTTGGCTGGGCAAAATATGTCGGCCTAGCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA
AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAG

Domains

Predicted by InterProScan.

Transketolase, pyrimidine binding domain (Transket_pyr)

(352-522)

Transketolase, C-terminal domain (Transketolase_C)

(552-652)

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(6-336)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

55.471

99.546

0.552