Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   ACB351_RS07450 Genome accession   NZ_CP167015
Coordinates   1449145..1451130 (-) Length   661 a.a.
NCBI ID   WP_011285064.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 11     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1444145..1456130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB351_RS07425 (ACB351_07425) - 1444157..1445407 (-) 1251 WP_011018075.1 glutamate-5-semialdehyde dehydrogenase -
  ACB351_RS07430 (ACB351_07430) proB 1445400..1446221 (-) 822 WP_002988886.1 glutamate 5-kinase -
  ACB351_RS07435 (ACB351_07435) - 1446285..1447913 (-) 1629 WP_002988883.1 hypothetical protein -
  ACB351_RS07440 (ACB351_07440) - 1447918..1448652 (-) 735 WP_002988881.1 ABC transporter ATP-binding protein -
  ACB351_RS07445 (ACB351_07445) - 1448686..1448952 (-) 267 WP_002988878.1 bacteriocin immunity protein -
  ACB351_RS07450 (ACB351_07450) recP/tkt 1449145..1451130 (-) 1986 WP_011285064.1 transketolase Machinery gene
  ACB351_RS07455 (ACB351_07455) fsa 1451348..1451992 (-) 645 WP_002983569.1 fructose-6-phosphate aldolase -
  ACB351_RS07460 (ACB351_07460) - 1452118..1453617 (-) 1500 WP_002988875.1 helix-turn-helix domain-containing protein -
  ACB351_RS07465 (ACB351_07465) - 1453607..1454953 (-) 1347 WP_021340874.1 FAD/NAD(P)-binding oxidoreductase -
  ACB351_RS07470 (ACB351_07470) - 1455062..1455763 (-) 702 WP_002988870.1 MIP/aquaporin family protein -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 71439.23 Da        Isoelectric Point: 4.6526

>NTDB_id=930934 ACB351_RS07450 WP_011285064.1 1449145..1451130(-) (recP/tkt) [Streptococcus pyogenes strain Isolate 11]
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVNHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAVYE
AEYPELAAEYQKAFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNFNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEV
KLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=930934 ACB351_RS07450 WP_011285064.1 1449145..1451130(-) (recP/tkt) [Streptococcus pyogenes strain Isolate 11]
ATGACATTTGATGCAATTGACCAGTTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC
TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA
CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTACAC
TTAGCTGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGT
GAATCACACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAG
AAGCTCACCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTAATCACTACACCTTTGCTTTGAATGGTGACGGT
GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA
TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTACGGTT
GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG
AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC
TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAA
CAGAGCGCTTTGCTCAAGGTCTTCAAGCGCGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGTTTATGAA
GCAGAATATCCAGAATTAGCAGCAGAATACCAAAAAGCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGA
ACTTGGTAGTTCAATGGCGAGTCGTGTATCCAGTCAACAAGCCATCCAACAAATCTCAGAACAAGTAGCCTCTTTCTGGG
GTGGATCAGCAGATCTTTCAGCATCTAACAACACAATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGC
CGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGT
TTACGGCGGAACCTTTTTTGTCTTCTCTAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAG
TTTATGTCATGACACATGATTCTATCGCTGTTGGTGAAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT
CGCTCAATGCCTAACTTTAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA
AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAACCTTCCAGTGCTTGAGGGCACAAAAGAATTGGCAGAAGATG
GTCTTAACAAAGGAGCTTACATCTTGTCAGAAGCCAAAGGCGACCTTGAAGGTATCTTGATTGCAACAGGTTCAGAAGTG
AAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCAGAAGGCATTCATGTGCGTGTCGTATCTATGCCATCACAAAATAT
CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT
CAAGCTTTGGCTGGGCAAAATATGTTGGCCTAGCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA
AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAG

Domains

Predicted by InterProScan.

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(6-335)

Transketolase, C-terminal domain (Transketolase_C)

(552-652)

Transketolase, pyrimidine binding domain (Transket_pyr)

(352-522)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

55.015

99.546

0.548