Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ACB355_RS06165 Genome accession   NZ_CP167011
Coordinates   1210786..1211448 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain Isolate 18     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1205786..1216448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB355_RS06145 (ACB355_06145) - 1206400..1206582 (-) 183 WP_023078840.1 hypothetical protein -
  ACB355_RS06150 (ACB355_06150) sodA 1206749..1207354 (-) 606 WP_023078860.1 superoxide dismutase SodA -
  ACB355_RS06155 (ACB355_06155) holA 1207451..1208491 (-) 1041 WP_023078852.1 DNA polymerase III subunit delta -
  ACB355_RS06160 (ACB355_06160) comEC/celB 1208562..1210805 (-) 2244 WP_115224604.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACB355_RS06165 (ACB355_06165) comEA/celA/cilE 1210786..1211448 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  ACB355_RS06170 (ACB355_06170) - 1211648..1212388 (-) 741 WP_021299345.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ACB355_RS06175 (ACB355_06175) - 1212506..1213282 (+) 777 WP_023078849.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ACB355_RS06180 (ACB355_06180) - 1213272..1213550 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  ACB355_RS06185 (ACB355_06185) - 1213574..1215574 (-) 2001 WP_030126409.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=930644 ACB355_RS06165 WP_002995626.1 1210786..1211448(-) (comEA/celA/cilE) [Streptococcus pyogenes strain Isolate 18]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=930644 ACB355_RS06165 WP_002995626.1 1210786..1211448(-) (comEA/celA/cilE) [Streptococcus pyogenes strain Isolate 18]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405