Detailed information NTG0930488

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ACB352_RS09305
• Genome accession: NZ_CP167009
• Coordinates: 1841445..1842212 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 22
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1836445..1847212

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB352_RS09290 (ACB352_09290)	hexB	1836963..1838945 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACB352_RS09295 (ACB352_09295)	-	1839040..1840191 (-)	1152	WP_003058754.1	site-specific integrase	-
ACB352_RS09300 (ACB352_09300)	-	1840440..1840583 (+)	144	WP_011185066.1	putative holin-like toxin	-
ACB352_RS09305 (ACB352_09305)	irvR	1841445..1842212 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
ACB352_RS09310 (ACB352_09310)	-	1842366..1842572 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
ACB352_RS09315 (ACB352_09315)	-	1842606..1842806 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
ACB352_RS09320 (ACB352_09320)	-	1842827..1843234 (+)	408	WP_002992501.1	hypothetical protein	-
ACB352_RS09325 (ACB352_09325)	-	1843247..1843369 (+)	123	WP_011285272.1	hypothetical protein	-
ACB352_RS09330 (ACB352_09330)	-	1843652..1844173 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
ACB352_RS09335 (ACB352_09335)	-	1844421..1844594 (+)	174	WP_000132665.1	hypothetical protein	-
ACB352_RS09340 (ACB352_09340)	-	1844812..1844985 (+)	174	WP_000074663.1	hypothetical protein	-
ACB352_RS09345 (ACB352_09345)	-	1845147..1845578 (+)	432	WP_136302445.1	hypothetical protein	-
ACB352_RS09350 (ACB352_09350)	-	1845680..1846012 (+)	333	WP_011285276.1	hypothetical protein	-
ACB352_RS09355 (ACB352_09355)	-	1846012..1846203 (+)	192	WP_021340709.1	hypothetical protein	-
ACB352_RS09360 (ACB352_09360)	-	1846215..1846544 (+)	330	WP_003058810.1	hypothetical protein	-
ACB352_RS09365 (ACB352_09365)	-	1846547..1846819 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=930488 ACB352_RS09305 WP_003058809.1 1841445..1842212(-) (irvR) [Streptococcus pyogenes strain Isolate 22]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=930488 ACB352_RS09305 WP_003058809.1 1841445..1842212(-) (irvR) [Streptococcus pyogenes strain Isolate 22]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4