Detailed information NTG0930394

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ACB353_RS09360
• Genome accession: NZ_CP167008
• Coordinates: 1863371..1864138 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 23
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1858371..1869138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB353_RS09345 (ACB353_09345)	-	1860083..1860400 (-)	318	WP_011285327.1	NUDIX domain-containing protein	-
ACB353_RS09350 (ACB353_09350)	-	1860966..1862117 (-)	1152	WP_003058754.1	site-specific integrase	-
ACB353_RS09355 (ACB353_09355)	-	1862366..1862509 (+)	144	WP_011185066.1	putative holin-like toxin	-
ACB353_RS09360 (ACB353_09360)	irvR	1863371..1864138 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
ACB353_RS09365 (ACB353_09365)	-	1864292..1864498 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
ACB353_RS09370 (ACB353_09370)	-	1864532..1864732 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
ACB353_RS09375 (ACB353_09375)	-	1864753..1865160 (+)	408	WP_002992501.1	hypothetical protein	-
ACB353_RS09380 (ACB353_09380)	-	1865173..1865295 (+)	123	WP_011285272.1	hypothetical protein	-
ACB353_RS09385 (ACB353_09385)	-	1865578..1866099 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
ACB353_RS09390 (ACB353_09390)	-	1866347..1866520 (+)	174	WP_000132665.1	hypothetical protein	-
ACB353_RS09395 (ACB353_09395)	-	1866738..1866911 (+)	174	WP_000074663.1	hypothetical protein	-
ACB353_RS09400 (ACB353_09400)	-	1867073..1867504 (+)	432	WP_136302445.1	hypothetical protein	-
ACB353_RS09405 (ACB353_09405)	-	1867606..1867938 (+)	333	WP_011285276.1	hypothetical protein	-
ACB353_RS09410 (ACB353_09410)	-	1867938..1868129 (+)	192	WP_021340709.1	hypothetical protein	-
ACB353_RS09415 (ACB353_09415)	-	1868141..1868470 (+)	330	WP_003058810.1	hypothetical protein	-
ACB353_RS09420 (ACB353_09420)	-	1868473..1868745 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=930394 ACB353_RS09360 WP_003058809.1 1863371..1864138(-) (irvR) [Streptococcus pyogenes strain Isolate 23]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=930394 ACB353_RS09360 WP_003058809.1 1863371..1864138(-) (irvR) [Streptococcus pyogenes strain Isolate 23]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGTTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4