Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ACB354_RS05990 Genome accession   NZ_CP167004
Coordinates   1125726..1126202 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain Isolate 28     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1120726..1131202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB354_RS05975 (ACB354_05975) fbp54 1121538..1123190 (+) 1653 WP_021340474.1 Rqc2 family fibronectin-binding protein Fbp54 -
  ACB354_RS05980 (ACB354_05980) - 1123250..1124497 (-) 1248 WP_021340481.1 tetratricopeptide repeat protein -
  ACB354_RS05985 (ACB354_05985) - 1124487..1125668 (-) 1182 WP_011184449.1 AI-2E family transporter -
  ACB354_RS05990 (ACB354_05990) mutX 1125726..1126202 (-) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ACB354_RS05995 (ACB354_05995) speh 1126806..1127516 (-) 711 WP_010922229.1 streptococcal pyrogenic exotoxin SpeH -
  ACB354_RS06000 (ACB354_06000) spei 1127542..1128219 (-) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  ACB354_RS06005 (ACB354_06005) - 1128488..1129240 (-) 753 WP_011184910.1 CHAP domain-containing protein -
  ACB354_RS06010 (ACB354_06010) - 1129362..1129589 (-) 228 WP_000609113.1 phage holin -
  ACB354_RS06015 (ACB354_06015) - 1129586..1129858 (-) 273 WP_002986916.1 hypothetical protein -
  ACB354_RS06020 (ACB354_06020) - 1129868..1130485 (-) 618 WP_011184056.1 DUF1366 domain-containing protein -
  ACB354_RS06025 (ACB354_06025) - 1130482..1130919 (-) 438 WP_011106643.1 DUF1617 family protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=929987 ACB354_RS05990 WP_002984880.1 1125726..1126202(-) (mutX) [Streptococcus pyogenes strain Isolate 28]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=929987 ACB354_RS05990 WP_002984880.1 1125726..1126202(-) (mutX) [Streptococcus pyogenes strain Isolate 28]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGAGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703