Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   ACB354_RS00680 Genome accession   NZ_CP167004
Coordinates   106515..106799 (+) Length   94 a.a.
NCBI ID   WP_027968839.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 28     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 101515..111799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB354_RS00655 (ACB354_00655) - 103461..103826 (+) 366 WP_002986560.1 DUF1033 family protein -
  ACB354_RS00660 (ACB354_00660) comGA 103919..104857 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  ACB354_RS00665 (ACB354_00665) comGB 104793..105827 (+) 1035 WP_011184088.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACB354_RS00670 (ACB354_00670) comGC 105829..106155 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ACB354_RS00675 (ACB354_00675) comGD 106130..106558 (+) 429 WP_011184089.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACB354_RS00680 (ACB354_00680) comGE 106515..106799 (+) 285 WP_027968839.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACB354_RS00685 (ACB354_00685) comGF 106792..107226 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACB354_RS00690 (ACB354_00690) comGG 107210..107536 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  ACB354_RS00695 (ACB354_00695) comGH 107634..108587 (+) 954 WP_021340467.1 class I SAM-dependent methyltransferase Machinery gene
  ACB354_RS00700 (ACB354_00700) - 108646..109842 (+) 1197 WP_002986533.1 acetate kinase -
  ACB354_RS00705 (ACB354_00705) - 110029..110337 (+) 309 WP_011017251.1 hypothetical protein -
  ACB354_RS00710 (ACB354_00710) proC 110420..111190 (-) 771 WP_011184092.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10617.54 Da        Isoelectric Point: 8.0182

>NTDB_id=929933 ACB354_RS00680 WP_027968839.1 106515..106799(+) (comGE) [Streptococcus pyogenes strain Isolate 28]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDTY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=929933 ACB354_RS00680 WP_027968839.1 106515..106799(+) (comGE) [Streptococcus pyogenes strain Isolate 28]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATACATAT
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383