Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ACB350_RS04420 Genome accession   NZ_CP166999
Coordinates   828752..829228 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain Isolate 34     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 823752..834228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB350_RS04395 (ACB350_04395) - 823793..824581 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  ACB350_RS04400 (ACB350_04400) - 824621..825727 (+) 1107 WP_030127488.1 FAD-binding oxidoreductase -
  ACB350_RS04405 (ACB350_04405) rfbA 825785..826654 (+) 870 WP_002992970.1 glucose-1-phosphate thymidylyltransferase RfbA -
  ACB350_RS04410 (ACB350_04410) - 826654..827247 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  ACB350_RS04415 (ACB350_04415) rfbB 827491..828531 (+) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  ACB350_RS04420 (ACB350_04420) mutX 828752..829228 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  ACB350_RS04425 (ACB350_04425) - 829286..830467 (+) 1182 WP_030127489.1 AI-2E family transporter -
  ACB350_RS04430 (ACB350_04430) - 830457..831704 (+) 1248 WP_030126713.1 tetratricopeptide repeat protein -
  ACB350_RS04435 (ACB350_04435) fbp54 831764..833416 (-) 1653 WP_030127490.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=929486 ACB350_RS04420 WP_002984880.1 828752..829228(+) (mutX) [Streptococcus pyogenes strain Isolate 34]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=929486 ACB350_RS04420 WP_002984880.1 828752..829228(+) (mutX) [Streptococcus pyogenes strain Isolate 34]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703