Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   ACB356_RS06465 Genome accession   NZ_CP166998
Coordinates   1297923..1299908 (-) Length   661 a.a.
NCBI ID   WP_002988876.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 35     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1292923..1304908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB356_RS06440 (ACB356_06440) - 1292935..1294185 (-) 1251 WP_011018075.1 glutamate-5-semialdehyde dehydrogenase -
  ACB356_RS06445 (ACB356_06445) proB 1294178..1294999 (-) 822 WP_002988886.1 glutamate 5-kinase -
  ACB356_RS06450 (ACB356_06450) - 1295063..1296691 (-) 1629 WP_002988883.1 hypothetical protein -
  ACB356_RS06455 (ACB356_06455) - 1296696..1297430 (-) 735 WP_002988881.1 ABC transporter ATP-binding protein -
  ACB356_RS06460 (ACB356_06460) - 1297464..1297730 (-) 267 WP_002988878.1 bacteriocin immunity protein -
  ACB356_RS06465 (ACB356_06465) recP/tkt 1297923..1299908 (-) 1986 WP_002988876.1 transketolase Machinery gene
  ACB356_RS06470 (ACB356_06470) fsa 1300126..1300770 (-) 645 WP_002983569.1 fructose-6-phosphate aldolase -
  ACB356_RS06475 (ACB356_06475) - 1300896..1302395 (-) 1500 WP_002988875.1 helix-turn-helix domain-containing protein -
  ACB356_RS06480 (ACB356_06480) - 1302385..1303731 (-) 1347 WP_011018081.1 FAD/NAD(P)-binding oxidoreductase -
  ACB356_RS06485 (ACB356_06485) - 1303840..1304541 (-) 702 WP_002988870.1 MIP/aquaporin family protein -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 71454.24 Da        Isoelectric Point: 4.6255

>NTDB_id=929418 ACB356_RS06465 WP_002988876.1 1297923..1299908(-) (recP/tkt) [Streptococcus pyogenes strain Isolate 35]
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWASKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAVYE
AEYPELAAEYQKAFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNFNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEV
KLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=929418 ACB356_RS06465 WP_002988876.1 1297923..1299908(-) (recP/tkt) [Streptococcus pyogenes strain Isolate 35]
ATGACATTTGATGCAATTGACCAGTTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC
TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA
CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTGCAT
TTAGCAGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGCTTCTAAAACACCAGGTCACCCAGAAGT
GAACCACACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAG
AAGCTCACCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGT
GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA
TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTACGGTT
GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG
AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC
TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAA
CAGAGCGCTTTGCTCAAGGCCTTCAAGCGCGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGTTTATGAA
GCAGAATATCCAGAATTAGCAGCAGAATACCAAAAAGCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGA
ACTTGGTAGTTCAATGGCGAGTCGTGTATCCAGTCAACAAGCCATCCAACAAATCTCAGAACAAGTAGCCTCTTTCTGGG
GTGGATCAGCAGATCTTTCAGCATCTAACAACACAATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGC
CGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGT
TTACGGCGGAACCTTTTTTGTCTTCTCAAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAG
TTTATGTCATGACACATGATTCTATCGCTGTTGGTGAAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT
CGCTCAATGCCTAACTTTAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA
AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAACCTTCCAGTGCTTGAGGGCACAAAAGAATTGGCAGAAGATG
GTCTTAACAAAGGAGCTTACATCTTGTCAGAAGCCAAAGGCGACCTTGAAGGTATCTTGATTGCAACAGGTTCAGAAGTG
AAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCAGAAGGCATTCATGTGCGTGTCGTATCTATGCCATCACAAAATAT
CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT
CAAGCTTTGGCTGGGCAAAATATGTTGGCCTAGCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA
AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAG

Domains

Predicted by InterProScan.

Transketolase, C-terminal domain (Transketolase_C)

(552-652)

Transketolase, pyrimidine binding domain (Transket_pyr)

(352-522)

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(6-335)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

55.015

99.546

0.548