Detailed information NTG0929250

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACA109_RS13385
• Genome accession: NZ_CP166872
• Coordinates: 2703289..2705397 (-)
• Length: 702 a.a.
• NCBI ID: WP_371256928.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 24EBSta0529
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2698289..2710397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACA109_RS13370 (ACA109_13370)	-	2700806..2701033 (+)	228	WP_000932073.1	FeoA family protein	-
ACA109_RS13375 (ACA109_13375)	feoB	2701045..2703039 (+)	1995	WP_000432894.1	ferrous iron transport protein B	-
ACA109_RS13380 (ACA109_13380)	-	2703052..2703222 (+)	171	WP_000111114.1	FeoB-associated Cys-rich membrane protein	-
ACA109_RS13385 (ACA109_13385)	clpE	2703289..2705397 (-)	2109	WP_371256928.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
ACA109_RS13390 (ACA109_13390)	-	2705760..2706281 (+)	522	WP_371256929.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
ACA109_RS13395 (ACA109_13395)	-	2706452..2707618 (-)	1167	WP_371256930.1	hydroxymethylglutaryl-CoA synthase	-
ACA109_RS13400 (ACA109_13400)	-	2707873..2709153 (+)	1281	WP_371256931.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACA109_RS13405 (ACA109_13405)	-	2709293..2709724 (-)	432	WP_000455861.1	CHAP domain-containing protein	-
ACA109_RS13410 (ACA109_13410)	-	2710115..2710333 (-)	219	WP_000011686.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78050.59 Da
• Isoelectric Point: 4.7097

>NTDB_id=929250 ACA109_RS13385 WP_371256928.1 2703289..2705397(-) (clpE) [Staphylococcus aureus strain 24EBSta0529]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKDIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLNKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=929250 ACA109_RS13385 WP_371256928.1 2703289..2705397(-) (clpE) [Staphylococcus aureus strain 24EBSta0529]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATTCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGACATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGAAACAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTGCTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAATGAAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGCCCTGAATTTCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTACAAGTAACATTAAATAAAAAAGGTATTACGATGAATGTT
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGCATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ACGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.056	91.595	0.44
clpE	Streptococcus pneumoniae Rx1	47.65	87.892	0.419
clpE	Streptococcus pneumoniae D39	47.65	87.892	0.419
clpE	Streptococcus pneumoniae R6	47.65	87.892	0.419
clpE	Streptococcus pneumoniae TIGR4	47.65	87.892	0.419
clpC	Lactococcus lactis subsp. cremoris KW2	46.044	90.028	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	44.037	93.162	0.41
clpC	Streptococcus thermophilus LMD-9	44.96	89.031	0.4
clpC	Streptococcus thermophilus LMG 18311	44.8	89.031	0.399
clpC	Streptococcus pneumoniae TIGR4	43.77	89.174	0.39
clpC	Streptococcus pneumoniae Rx1	43.942	88.177	0.387
clpC	Streptococcus pneumoniae D39	43.942	88.177	0.387
clpC	Streptococcus mutans UA159	43.902	87.607	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.376	88.746	0.376