Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   AB9A07_RS06270 Genome accession   NZ_CP166018
Coordinates   1283408..1285417 (+) Length   669 a.a.
NCBI ID   WP_000516264.1    Uniprot ID   A0A641ACF7
Organism   Staphylococcus aureus strain GIMC7004:SaO-15 isolate GIMC7004:SaO-15     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1278408..1290417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB9A07_RS06255 (AB9A07_06270) - 1279591..1279956 (+) 366 WP_000282386.1 RicAFT regulatory complex protein RicA family protein -
  AB9A07_RS06260 (AB9A07_06275) thiW 1279983..1280474 (+) 492 WP_000842277.1 energy coupling factor transporter S component ThiW -
  AB9A07_RS06265 (AB9A07_06280) hexA 1280777..1283395 (+) 2619 WP_000073352.1 DNA mismatch repair protein MutS Machinery gene
  AB9A07_RS06270 (AB9A07_06285) hexB 1283408..1285417 (+) 2010 WP_000516264.1 DNA mismatch repair endonuclease MutL Machinery gene
  AB9A07_RS06275 (AB9A07_06290) - 1285423..1285965 (+) 543 WP_001077635.1 glycerol-3-phosphate responsive antiterminator -
  AB9A07_RS06280 (AB9A07_06295) - 1286440..1287258 (+) 819 WP_001103743.1 MIP/aquaporin family protein -
  AB9A07_RS06285 (AB9A07_06300) glpK 1287387..1288883 (+) 1497 WP_000417369.1 glycerol kinase GlpK -

Sequence

Protein


Download         Length: 669 a.a.        Molecular weight: 76897.11 Da        Isoelectric Point: 5.0519

>NTDB_id=927997 AB9A07_RS06270 WP_000516264.1 1283408..1285417(+) (hexB) [Staphylococcus aureus strain GIMC7004:SaO-15 isolate GIMC7004:SaO-15]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSKPFMVENQNDEIVIREDSYNPFV
TKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDDTSVQNYENKASDDYYDVNDIKGTKSKDPKRRIPY
MEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIM
LEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREA
EDPFTCPHGRPIIINFSKYELEKLFKRVM

Nucleotide


Download         Length: 2010 bp        

>NTDB_id=927997 AB9A07_RS06270 WP_000516264.1 1283408..1285417(+) (hexB) [Staphylococcus aureus strain GIMC7004:SaO-15 isolate GIMC7004:SaO-15]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAACAGAATGGCAATGAGCCATCCGGACATTCGAATAGC
ACTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGCTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATACCAATTGATTGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCGAAAAAAAATAAAGTGTTACA
TTCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAATCAAGAGAAGACGTTTTCATCTGAAG
AAAGTAACAGTAAGCCATTTATGGTAGAAAATCAAAACGATGAAATAGTTATAAGAGAAGATTCATATAATCCATTCGTA
ACGAAAACGTCTGAAAGTTTAATAGCTGATGATGAATCTTCCGGTTATAATAATACACGTGAAAAAGATGAAGACTACTT
CAAAAAGCAACAAGAAATTCTACAAGAAATGGATCAAACATTTGATTCGAATGACGATACATCTGTGCAAAATTATGAGA
ATAAAGCGTCTGATGATTATTATGATGTAAACGATATTAAAGGAACAAAAAGTAAAGACCCTAAACGAAGAATTCCATAT
ATGGAAATTGTTGGCCAAGTACATGGAACGTATATTATTGCTCAAAATGAATTTGGCATGTACATGATTGACCAGCATGC
AGCTCAAGAAAGAATAAAATATGAATATTTTCGAGATAAAATAGGTGAAGTTACCAATGAAGTACAAGATTTATTAATCC
CGTTAACATTTCATTTTTCAAAAGATGAACAATTAGTCATTGATCAATATAAAAATGAGCTTCAACAAGTAGGTATCATG
TTAGAACATTTTGGTGGTCATGATTATATTGTAAGTAGCTATCCAGTTTGGTTCCCTAAAGATGAAGTAGAAGAAATTAT
TAAAGATATGATTGAGCTAATTTTGGAAGAGAAAAAAGTAGATATCAAAAAATTACGTGAAGATGTAGCAATCATGATGT
CATGTAAAAAATCTATTAAAGCGAATCATTATTTACAAAAACATGAAATGTCTGATTTAATTGATCAATTAAGAGAAGCG
GAAGATCCATTTACATGTCCACATGGTCGTCCAATTATCATTAATTTTTCAAAATACGAATTAGAAAAATTATTTAAGCG
TGTGATGTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(483-625)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641ACF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

40.828

100

0.413