Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   AB5J51_RS29305 Genome accession   NZ_CP165727
Coordinates   6367723..6370704 (+) Length   993 a.a.
NCBI ID   WP_053785780.1    Uniprot ID   -
Organism   Streptomyces sp. R33     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 6362723..6375704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB5J51_RS29285 (AB5J51_29325) - 6363674..6364657 (+) 984 WP_053785776.1 TerC/Alx family metal homeostasis membrane protein -
  AB5J51_RS29290 (AB5J51_29330) - 6364677..6366011 (-) 1335 WP_136225990.1 MFS transporter -
  AB5J51_RS29295 (AB5J51_29335) - 6366172..6366828 (-) 657 WP_053785778.1 MBL fold metallo-hydrolase -
  AB5J51_RS29300 (AB5J51_29340) - 6366838..6367536 (-) 699 WP_053785779.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  AB5J51_RS29305 (AB5J51_29345) uvrA 6367723..6370704 (+) 2982 WP_053785780.1 excinuclease ABC subunit UvrA Machinery gene
  AB5J51_RS29310 (AB5J51_29350) - 6370757..6371404 (-) 648 WP_136225962.1 NAD(P)-dependent oxidoreductase -
  AB5J51_RS29315 (AB5J51_29355) - 6371468..6372073 (+) 606 WP_053785782.1 TetR/AcrR family transcriptional regulator -
  AB5J51_RS29320 (AB5J51_29360) - 6372063..6372950 (-) 888 WP_369779039.1 carbohydrate kinase -
  AB5J51_RS29325 (AB5J51_29365) - 6373055..6373486 (+) 432 WP_053785784.1 Rieske (2Fe-2S) protein -
  AB5J51_RS29330 (AB5J51_29370) - 6373510..6374466 (-) 957 WP_053785785.1 hypothetical protein -
  AB5J51_RS29335 (AB5J51_29375) - 6374715..6375338 (+) 624 WP_369779040.1 papain-like cysteine protease family protein -

Sequence

Protein


Download         Length: 993 a.a.        Molecular weight: 109293.47 Da        Isoelectric Point: 7.5605

>NTDB_id=927680 AB5J51_RS29305 WP_053785780.1 6367723..6370704(+) (uvrA) [Streptomyces sp. R33]
MTDRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECRRPISRQSPQAIVDKVLALPEGSRFQVLSPLVRERK
GEFVDLFSDLQTKGYSRARVDGETIQLSEPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVILDFVDL
AEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPECTGIGTRMEVDPELIIPDEDKSLDEGAVSPWSLGHTK
DYFQRLIGALAGELGFRTDIPWAGLPLRARKALLYGHKTQIEVRYRNRYGRERAYTTAFEGAVPFVKRRHAESESDASRE
RFEGYMREVPCPTCEGTRLKPIVLAVTVMEKSIAEVAAMSISECADFLGRMRLDARDKKIAERVLKEVNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WVVDIGPGAGEHGGKVVHSGSLKELLKNGDSMTGQYLSGKRSIAVPDIRRPVNGDRKLTVHGAKENNLRDIDVSFPLGVL
TAVTGVSGSGKSTLVNDILYTHLARELNGARSVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLFA
ETMEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGDRYNRETLEVHYKGKSIAEVLNMPIEEA
LDFFEAVPTISRHLRTLNEVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLIKVLS
GLVDKGNSVIVIEHNLDVIKTADWVIDMGPEGGYGGGLVVAEGTPEQVASVGASHTGKFLRDILGAERVSDAVSLVTPPK
KAAAKRTAAKKTATPAKKAAAPAKKAPARARKA

Nucleotide


Download         Length: 2982 bp        

>NTDB_id=927680 AB5J51_RS29305 WP_053785780.1 6367723..6370704(+) (uvrA) [Streptomyces sp. R33]
GTGACCGACCGTCTCATCGTTCGTGGCGCTCGCGAGCACAACCTCAAGAACGTCTCGCTCGACCTGCCCCGCGACTCACT
CATCGTCTTCACCGGACTCTCCGGTTCGGGCAAGTCCTCCCTGGCCTTCGACACGATCTTCGCCGAGGGCCAGCGCCGCT
ACGTCGAGTCGCTCTCGTCGTACGCCCGCCAGTTCCTGGGGCAGATGGACAAGCCCGACGTGGACTTCATCGAGGGGCTC
TCGCCGGCCGTCTCGATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTCCGCCTGCTCTTCGCGCGCATCGGCAAGCCCCACTGCCCGGAGTGCCGCCGCCCCATCTCGCGCCAGTCGCCGC
AGGCGATCGTCGACAAGGTGCTCGCACTCCCCGAGGGCAGCCGCTTCCAGGTGCTCTCGCCACTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCTCCGACCTCCAGACCAAGGGCTACAGCCGGGCGCGGGTGGACGGGGAGACCATCCAGCT
CTCCGAGCCGCCGACGCTGAAGAAGCAGGAGAAGCACACGATCGAGGTGGTCGTCGACCGCCTCACCGTCAAGGACAGCG
CCAAGCGCCGGCTCACCGACTCCGTGGAGACCGCCCTCGGGCTCTCCGGCGGCATGGTGATCCTGGACTTCGTCGACCTC
GCCGAGGACGACCCCGAGCGTGAGCGGATGTACTCCGAGCACCTCTACTGCCCGTACGACGACCTGTCCTTCGAGGAGCT
GGAGCCGCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCCGAGTGCACCGGCATCGGTACGCGCATGGAAGTGG
ACCCGGAGCTGATCATTCCGGACGAGGACAAGTCCCTGGACGAGGGCGCGGTCTCCCCGTGGTCCCTCGGCCACACCAAG
GACTACTTCCAGCGGCTGATCGGCGCGCTCGCCGGCGAGCTGGGCTTCCGTACGGACATCCCGTGGGCCGGGCTGCCGCT
GCGGGCGAGGAAGGCCCTGCTGTACGGGCACAAGACGCAGATCGAGGTCCGCTACCGCAACCGGTACGGGCGGGAGCGGG
CGTACACGACGGCCTTCGAGGGCGCCGTGCCGTTCGTCAAGCGCCGGCACGCCGAGTCCGAGAGCGACGCCAGCCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCGACCTGTGAGGGCACCCGGCTCAAGCCGATCGTGCTCGCGGTGAC
GGTGATGGAGAAGTCCATCGCCGAGGTCGCCGCGATGTCGATCAGCGAGTGCGCGGACTTCCTCGGGCGGATGCGGCTCG
ACGCCCGCGACAAGAAGATCGCCGAGCGGGTCCTGAAGGAGGTCAACGAGCGGCTCCGCTTCCTCGTCGACGTCGGCCTG
GACTACCTCTCGCTGAACCGCGCCGCCGGCACCCTGTCGGGCGGCGAGGCCCAGCGCATCCGCCTCGCCACCCAGATCGG
CTCCGGCCTGGTCGGCGTGCTGTACGTCCTGGACGAGCCCTCCATCGGGCTGCACCAGCGGGACAACCACCGGCTGATCG
AGACGCTGGTGCGGCTGCGGGACATGGGCAACACCCTGATCGTCGTCGAGCACGACGAGGACACGATCAAGGTGGCCGAC
TGGGTCGTGGACATCGGCCCGGGCGCCGGCGAGCACGGCGGCAAGGTCGTGCACAGCGGCTCGCTGAAGGAGCTGCTGAA
GAACGGCGACTCGATGACCGGGCAGTACCTGTCCGGGAAGCGGTCCATCGCGGTGCCGGACATCCGCCGGCCCGTCAACG
GGGACCGGAAGCTGACCGTCCACGGCGCCAAGGAGAACAACCTGCGGGACATCGACGTGTCCTTCCCGCTGGGCGTGCTC
ACGGCGGTGACGGGCGTGTCGGGATCGGGCAAGTCGACGCTGGTCAACGACATCCTGTACACGCACCTGGCGCGCGAGCT
GAACGGCGCCCGCTCGGTGCCGGGACGGCACACGCGGGTGGACGGGGACGACCTCGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCGATCGGGCGGACCCCGCGGTCCAACCCGGCGACGTACACGGGCGTCTTCGACCACGTGCGCAAGCTCTTCGCG
GAGACGATGGAGGCGAAGGTGCGCGGCTACCTGCCGGGCCGCTTCTCCTTCAACGTGAAGGGCGGCCGGTGCGAGAACTG
CTCCGGCGACGGCACGATCAAGATCGAGATGAACTTCCTGCCGGACGTGTACGTCCCGTGCGAGGTCTGCCACGGCGACC
GGTACAACCGGGAGACGCTGGAGGTCCACTACAAGGGCAAGTCCATCGCCGAGGTCCTGAACATGCCGATCGAGGAGGCT
CTGGACTTCTTCGAGGCGGTGCCGACGATCTCGCGCCACCTGCGGACGCTGAACGAGGTGGGGCTGGGCTACGTCCGGCT
CGGCCAGTCGGCGCCGACGCTCTCGGGCGGTGAGGCGCAGCGCGTGAAGCTGGCGTCGGAGCTGCAGAAGCGGTCGACGG
GGCGGACGGTCTACGTGCTGGACGAGCCGACGACGGGTCTGCACTTCGAGGACATCTCGAAGCTGATCAAGGTGCTGTCG
GGGCTGGTGGACAAGGGCAACTCGGTGATCGTCATCGAGCACAACCTGGACGTCATCAAGACCGCGGACTGGGTGATCGA
CATGGGCCCGGAGGGCGGTTACGGGGGCGGTCTGGTGGTCGCCGAGGGCACGCCGGAGCAGGTCGCGTCGGTGGGCGCGA
GCCACACGGGCAAGTTCCTGCGGGACATCCTGGGGGCGGAACGGGTCTCGGACGCCGTCTCGCTCGTGACCCCGCCGAAG
AAGGCCGCCGCCAAGCGGACTGCGGCCAAGAAGACGGCGACCCCGGCCAAGAAGGCTGCGGCCCCGGCCAAGAAGGCTCC
GGCCCGGGCCCGCAAGGCCTAG

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

ABC transporter (ABC_tran)

(628-864)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.257

95.77

0.539
  uvrA Streptococcus pneumoniae TIGR4

56.257

95.77

0.539
  uvrA Streptococcus pneumoniae D39

56.257

95.77

0.539