Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VRS73_RS06575 Genome accession   NZ_CP142602
Coordinates   1327101..1327739 (+) Length   212 a.a.
NCBI ID   WP_003180627.1    Uniprot ID   A0A6I7TLB4
Organism   Bacillus paralicheniformis strain A5     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1322101..1332739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VRS73_RS06545 (VRS73_06545) - 1322748..1323815 (+) 1068 WP_020450934.1 ABC transporter ATP-binding protein -
  VRS73_RS06550 (VRS73_06550) - 1323817..1324740 (+) 924 WP_020450935.1 ABC transporter ATP-binding protein -
  VRS73_RS06555 (VRS73_06555) - 1324971..1325549 (+) 579 WP_003180619.1 GNAT family N-acetyltransferase -
  VRS73_RS06560 (VRS73_06560) spxA 1325727..1326122 (+) 396 WP_003180621.1 transcriptional regulator SpxA -
  VRS73_RS06565 (VRS73_06565) - 1326153..1326815 (-) 663 WP_020450936.1 TerC family protein -
  VRS73_RS06570 (VRS73_06570) - 1326994..1327119 (+) 126 Protein_1246 hypothetical protein -
  VRS73_RS06575 (VRS73_06575) mecA 1327101..1327739 (+) 639 WP_003180627.1 adaptor protein MecA Regulator
  VRS73_RS06580 (VRS73_06580) - 1327977..1329281 (+) 1305 WP_020450937.1 glycosyl hydrolase family 8 -
  VRS73_RS06585 (VRS73_06585) - 1329504..1330520 (+) 1017 WP_041817434.1 tripartite tricarboxylate transporter substrate binding protein -
  VRS73_RS06590 (VRS73_06590) - 1330623..1331078 (+) 456 WP_048350052.1 tripartite tricarboxylate transporter TctB family protein -
  VRS73_RS06595 (VRS73_06595) - 1331101..1332606 (+) 1506 WP_020450940.1 tripartite tricarboxylate transporter permease -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 25044.99 Da        Isoelectric Point: 4.1840

>NTDB_id=926225 VRS73_RS06575 WP_003180627.1 1327101..1327739(+) (mecA) [Bacillus paralicheniformis strain A5]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSISGCQTTLYSHENRYYLFV
DFSELPDEEVENQLSILLEYASESKTTIHMLKEYGTLIAADHALHTIKKHFA

Nucleotide


Download         Length: 639 bp        

>NTDB_id=926225 VRS73_RS06575 WP_003180627.1 1327101..1327739(+) (mecA) [Bacillus paralicheniformis strain A5]
ATGGAAATCGAAAGAATAAACGAACATACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGATAAGGGATTGGAAATCATTGTGACAAGAGCTCAGCTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAGTTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTATCAGCGGCTGCCAAACGACATTGTACTCTCACGAGAACCGCTATTATTTATTCGTG
GATTTCAGTGAACTGCCCGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAGTATGCCTCAGAATCAAAGACGAC
GATTCATATGCTGAAAGAGTATGGAACACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTCGCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I7TLB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

82.028

100

0.84