Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   VP459_RS10980 Genome accession   NZ_CP142600
Coordinates   2285919..2286635 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain M19060305     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2280919..2291635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VP459_RS10960 (VP459_10965) - 2282012..2282962 (+) 951 WP_000790322.1 LacI family DNA-binding transcriptional regulator -
  VP459_RS10965 (VP459_10970) - 2283111..2284595 (+) 1485 WP_000141410.1 sucrose-6-phosphate hydrolase -
  VP459_RS10970 (VP459_10975) - 2284592..2285551 (+) 960 WP_001253301.1 carbohydrate kinase -
  VP459_RS10975 (VP459_10980) - 2285740..2285847 (-) 108 WP_031789494.1 hypothetical protein -
  VP459_RS10980 (VP459_10985) agrA 2285919..2286635 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  VP459_RS10985 (VP459_10990) agrC 2286654..2287946 (-) 1293 WP_001670396.1 quorum-sensing sensor histidine kinase AgrC -
  VP459_RS10990 (VP459_10995) agrD 2287971..2288111 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  VP459_RS10995 (VP459_11000) agrB 2288108..2288677 (-) 570 WP_001105713.1 accessory gene regulator AgrB -
  VP459_RS11000 hld 2288967..2289047 (+) 81 WP_000046022.1 delta-hemolysin -
  VP459_RS11005 (VP459_11010) - 2289646..2290431 (-) 786 WP_000867943.1 carbon-nitrogen family hydrolase -
  VP459_RS11010 (VP459_11015) - 2290701..2291327 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=926150 VP459_RS10980 WP_000688492.1 2285919..2286635(-) (agrA) [Staphylococcus aureus strain M19060305]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=926150 VP459_RS10980 WP_000688492.1 2285919..2286635(-) (agrA) [Staphylococcus aureus strain M19060305]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCATAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATCGAATCTATAG
ATTCGAAAGAGCGCATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1