Detailed information    

insolico Bioinformatically predicted

Overview

Name   braS   Type   Regulator
Locus tag   VP459_RS07805 Genome accession   NZ_CP142600
Coordinates   1661832..1662719 (+) Length   295 a.a.
NCBI ID   WP_000143420.1    Uniprot ID   A0A2S6DP21
Organism   Staphylococcus aureus strain M19060305     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1656832..1667719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VP459_RS07775 (VP459_07780) - 1657638..1658399 (+) 762 WP_000323451.1 alpha/beta hydrolase family protein -
  VP459_RS07780 (VP459_07785) - 1658645..1659100 (+) 456 WP_000106184.1 MarR family winged helix-turn-helix transcriptional regulator -
  VP459_RS07785 (VP459_07790) - 1659222..1659323 (+) 102 WP_000731972.1 SE2200 family small protein -
  VP459_RS07790 (VP459_07795) - 1659383..1660732 (-) 1350 WP_000953732.1 alkaline phosphatase -
  VP459_RS07795 (VP459_07800) - 1660930..1661130 (+) 201 WP_000604723.1 hypothetical protein -
  VP459_RS07800 (VP459_07805) braR 1661156..1661821 (+) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  VP459_RS07805 (VP459_07810) braS 1661832..1662719 (+) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  VP459_RS07810 (VP459_07815) - 1662827..1663582 (+) 756 WP_000923768.1 ABC transporter ATP-binding protein -
  VP459_RS07815 (VP459_07820) - 1663579..1665579 (+) 2001 WP_000776746.1 ABC transporter permease -
  VP459_RS07820 (VP459_07825) - 1666243..1666356 (+) 114 WP_072384844.1 hypothetical protein -
  VP459_RS07825 (VP459_07830) - 1666738..1666998 (+) 261 WP_072434822.1 hypothetical protein -
  VP459_RS07830 (VP459_07835) - 1667008..1667505 (+) 498 WP_101244946.1 glutathione peroxidase -
  VP459_RS07835 (VP459_07840) - 1667613..1667701 (-) 89 Protein_1531 hypothetical protein -

Sequence

Protein


Download         Length: 295 a.a.        Molecular weight: 34045.32 Da        Isoelectric Point: 5.8962

>NTDB_id=926146 VP459_RS07805 WP_000143420.1 1661832..1662719(+) (braS) [Staphylococcus aureus strain M19060305]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide


Download         Length: 888 bp        

>NTDB_id=926146 VP459_RS07805 WP_000143420.1 1661832..1662719(+) (braS) [Staphylococcus aureus strain M19060305]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(191-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DP21

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braS Staphylococcus aureus N315

99.322

100

0.993