Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   AB2U05_RS08985 Genome accession   NZ_CP163445
Coordinates   2144308..2147220 (-) Length   970 a.a.
NCBI ID   WP_045702761.1    Uniprot ID   A0A0F2T9F7
Organism   Streptomyces sp. Y1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2139308..2152220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB2U05_RS08965 (AB2U05_08965) yvcK 2139471..2140568 (-) 1098 WP_063773584.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  AB2U05_RS08970 (AB2U05_08970) rapZ 2140640..2141524 (-) 885 WP_244179003.1 RNase adapter RapZ -
  AB2U05_RS08975 (AB2U05_08975) uvrC 2141643..2143682 (-) 2040 WP_369182961.1 excinuclease ABC subunit UvrC -
  AB2U05_RS08980 (AB2U05_08980) - 2143749..2144192 (-) 444 WP_369182962.1 Rieske (2Fe-2S) protein -
  AB2U05_RS08985 (AB2U05_08985) uvrA 2144308..2147220 (-) 2913 WP_045702761.1 excinuclease ABC subunit UvrA Machinery gene
  AB2U05_RS08990 (AB2U05_08990) - 2147489..2148220 (+) 732 WP_045702760.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  AB2U05_RS08995 (AB2U05_08995) - 2148269..2148922 (+) 654 WP_045702758.1 MBL fold metallo-hydrolase -
  AB2U05_RS09000 (AB2U05_09000) - 2148973..2149383 (-) 411 WP_045702756.1 type II toxin-antitoxin system VapC family toxin -
  AB2U05_RS09005 (AB2U05_09005) - 2149380..2149610 (-) 231 WP_045702754.1 antitoxin -
  AB2U05_RS09010 (AB2U05_09010) - 2149701..2150681 (-) 981 WP_369182963.1 TerC family protein -
  AB2U05_RS09015 (AB2U05_09015) - 2150874..2151452 (-) 579 WP_045702750.1 TerD family protein -

Sequence

Protein


Download         Length: 970 a.a.        Molecular weight: 107108.60 Da        Isoelectric Point: 7.1660

>NTDB_id=925671 AB2U05_RS08985 WP_045702761.1 2144308..2147220(-) (uvrA) [Streptomyces sp. Y1]
MADRLVVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTNRNPRSTVGTITEVYDYLRLLFARIGKPHCPHCGRPIAKQSPQAIVDKVLELSEGTRFQVLSPVVRERK
GEFVDLFADLQSKGYSRARVDGETIQLAEPPKLKKQEKHTVEVVVDRLTVKESAKRRLTDSVETALRLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDVSFEELEPRSFSFNSPFGACPDCSGLGNRMEVDPELVVPDPERSLDEGAIHPWSAGHAK
EYFQRLIDALAEELGFRTDIPWAGLPARAKKALLYGHKHQVQVRYRNRFGRERSYSTGFEGAVPFIQRRHTEAESDSSRE
RFEGYMREVPCPTCQGTRLKPVVLAVTVEEKSIADVSSMSISDCAEFLGAMKLNDRDKQIAERVLKEVNERLRFLVDVGL
DYLSLDRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDIGNTLIVVEHDEDTIKTAD
WVVDIGPGAGEHGGKVVHSGSLKQLLTNKESLTGQYLSGKRFIPVPAARRERDKKRQLTVHGAREHNLKDVTVGFPLGTF
TAITGVSGSGKSTLVNDILYTHLARELNGARSVPGRHTRITGTDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRRLFA
ETQEAKVRGYLPGRFSFNVKGGRCENCTGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLDMPIEEA
LAFFEAVPAIARHLRTLNDVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLIKVLS
GLVDKGNTVIVIEHNLDVIKTADWVVDMGPEGGSGGGTVVAEGTPEQIAAVSESHTGKFLRDILPGDFADAPVAAPAKRA
PRKRAVAAKK

Nucleotide


Download         Length: 2913 bp        

>NTDB_id=925671 AB2U05_RS08985 WP_045702761.1 2144308..2147220(-) (uvrA) [Streptomyces sp. Y1]
GTGGCCGACCGCCTCGTCGTCCGCGGTGCACGCGAGCACAACCTGAAGAACGTCTCGCTCGACCTGCCCCGCGACTCCCT
CATCGTCTTCACGGGCCTCTCCGGCTCCGGCAAGTCCTCGCTCGCCTTCGACACGATCTTCGCCGAGGGCCAGCGCCGCT
ACGTCGAGTCGCTGTCCTCCTACGCCCGCCAGTTCCTGGGCCAGATGGACAAGCCCGACGTGGACTTCATCGAAGGCCTC
TCCCCGGCCGTCTCGATCGACCAGAAGTCCACCAACCGCAACCCCCGCTCGACCGTCGGCACCATCACCGAGGTGTACGA
CTACCTGCGCCTGCTGTTCGCCCGGATCGGCAAGCCGCACTGCCCGCACTGCGGCCGCCCGATCGCCAAGCAGTCGCCGC
AGGCGATCGTCGACAAGGTCCTGGAGCTCTCCGAGGGCACCCGCTTCCAGGTGCTCAGCCCGGTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTGTTCGCCGACCTCCAGTCCAAGGGCTACTCCCGCGCCCGCGTCGACGGCGAGACGATCCAGCT
CGCCGAGCCGCCGAAGCTGAAGAAGCAGGAGAAGCACACCGTCGAGGTGGTCGTCGACCGCCTGACCGTCAAGGAGAGCG
CCAAGCGGCGGCTCACCGACTCGGTGGAGACGGCCCTGCGGCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCGGAGGACGACCCGGAGCGCGAGCGGATGTACTCCGAGCACCTGTACTGCCCGTACGACGACGTGTCGTTCGAGGAGCT
GGAGCCGCGCTCGTTCTCCTTCAACTCGCCGTTCGGCGCCTGCCCGGACTGCTCGGGCCTGGGCAACCGGATGGAGGTCG
ACCCGGAGCTCGTCGTGCCGGACCCGGAGCGCTCGCTGGACGAGGGCGCGATCCACCCCTGGTCGGCCGGGCACGCCAAG
GAGTACTTCCAGCGCCTGATCGACGCGCTGGCCGAGGAGCTGGGCTTCCGCACCGACATCCCCTGGGCCGGGCTGCCGGC
CCGCGCCAAGAAGGCGCTGCTGTACGGGCACAAGCACCAGGTGCAGGTCCGCTACCGCAACCGCTTCGGCCGCGAGCGCT
CGTACAGCACCGGCTTCGAGGGCGCGGTGCCGTTCATCCAGCGCCGGCACACCGAGGCGGAGAGCGACAGCAGCCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCGACCTGCCAGGGCACCCGGCTCAAGCCGGTGGTGCTGGCGGTCAC
CGTCGAGGAGAAGTCGATCGCCGACGTCTCGTCGATGTCGATCAGCGACTGCGCCGAGTTCCTGGGCGCGATGAAGCTCA
ACGACCGGGACAAGCAGATCGCCGAGCGCGTCCTGAAGGAGGTCAACGAGCGGCTGCGCTTCCTGGTCGACGTCGGCCTG
GACTACCTCTCGCTGGACCGCGCGGCCGGCACCCTGTCCGGCGGCGAGGCGCAGCGCATCCGGCTGGCCACCCAGATCGG
CTCCGGCCTGGTCGGCGTGCTGTACGTGCTGGACGAGCCGTCGATCGGCCTGCACCAGCGGGACAACCACCGGCTGATCG
AGACGCTGGTGCGGCTGCGCGACATCGGCAACACCCTGATCGTGGTCGAGCACGACGAGGACACCATCAAGACCGCGGAC
TGGGTGGTGGACATCGGCCCGGGCGCCGGCGAGCACGGCGGCAAGGTGGTGCACTCCGGTTCGCTGAAGCAGCTGCTCAC
CAACAAGGAGTCGCTGACCGGCCAGTACCTGTCCGGCAAGAGGTTCATCCCGGTCCCGGCCGCGCGCCGCGAGCGGGACA
AGAAGCGGCAGTTGACGGTCCACGGCGCCCGCGAGCACAACCTCAAGGACGTCACGGTCGGCTTCCCGCTCGGCACCTTC
ACGGCGATCACCGGCGTCTCCGGCTCCGGCAAGTCGACGCTGGTCAACGACATCCTCTACACCCACCTCGCCCGGGAGCT
GAACGGCGCCCGCAGCGTGCCCGGCCGGCACACCCGGATCACCGGCACGGACCTGGTGGACAAGGTGGTGCACGTCGACC
AGTCGCCGATCGGCCGCACCCCGCGCTCCAACCCGGCCACCTACACCGGGGTGTTCGACCACGTGCGCCGGCTGTTCGCG
GAGACGCAGGAGGCCAAGGTCCGCGGCTACCTGCCCGGCCGGTTCTCGTTCAACGTGAAGGGCGGCCGCTGCGAGAACTG
CACCGGTGACGGCACCATCAAGATCGAGATGAACTTCCTGCCGGACGTCTACGTGCCGTGCGAGGTGTGCCACGGCGCCC
GGTACAACCGGGAGACGCTGGAGGTGCACTACAAGGGCAAGTCCATCGCCGAGGTGCTGGACATGCCGATCGAGGAGGCG
CTGGCGTTCTTCGAGGCCGTCCCGGCGATCGCCCGCCACCTGCGGACGCTCAACGACGTCGGCCTCGGCTACGTCCGCCT
CGGCCAGTCCGCGCCGACGCTGTCCGGCGGCGAGGCGCAGCGCGTCAAGCTCGCCTCGGAGCTGCAGAAGCGCTCCACCG
GGCGGACGGTCTACGTGCTGGACGAGCCCACCACCGGTCTGCACTTCGAGGACATCAGCAAGCTGATCAAGGTGCTCAGC
GGGCTGGTCGACAAGGGCAACACGGTGATCGTGATCGAGCACAACCTCGACGTGATCAAGACCGCCGACTGGGTCGTCGA
CATGGGCCCCGAGGGCGGTTCCGGCGGCGGCACGGTGGTCGCCGAGGGCACCCCGGAGCAGATCGCGGCCGTCTCGGAGA
GCCACACCGGCAAGTTCCTCCGGGACATCCTGCCGGGCGACTTCGCGGACGCCCCGGTCGCCGCCCCCGCCAAGCGGGCG
CCGCGCAAGCGGGCCGTCGCGGCGAAGAAGTAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(628-864)

UvrA interaction domain (UvrA_inter)

(131-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2T9F7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.46

97.423

0.56
  uvrA Streptococcus pneumoniae TIGR4

57.46

97.423

0.56
  uvrA Streptococcus pneumoniae D39

57.46

97.423

0.56