Detailed information NTG0925441

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AB5J52_RS26385
• Genome accession: NZ_CP163441
• Coordinates: 5822099..5824624 (+)
• Length: 841 a.a.
• NCBI ID: WP_234544478.1
• Uniprot ID: -
• Organism: Streptomyces sp. R39
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 5817099..5829624

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB5J52_RS26355 (AB5J52_26355)	-	5818404..5819021 (+)	618	WP_369228219.1	hypothetical protein	-
AB5J52_RS26360 (AB5J52_26360)	-	5819143..5819328 (+)	186	WP_181806392.1	hypothetical protein	-
AB5J52_RS26365 (AB5J52_26365)	-	5819491..5819913 (+)	423	WP_268208284.1	BlaI/MecI/CopY family transcriptional regulator	-
AB5J52_RS26370 (AB5J52_26370)	-	5819923..5820456 (+)	534	WP_181806391.1	amino-acid N-acetyltransferase	-
AB5J52_RS26375 (AB5J52_26375)	-	5820734..5821069 (+)	336	WP_181806390.1	Lsr2 family protein	-
AB5J52_RS26380 (AB5J52_26380)	-	5821048..5821668 (-)	621	WP_369224296.1	SCO3374 family protein	-
AB5J52_RS26385 (AB5J52_26385)	clpC	5822099..5824624 (+)	2526	WP_234544478.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
AB5J52_RS26390 (AB5J52_26390)	-	5824933..5825535 (-)	603	WP_234544477.1	HAD family acid phosphatase	-
AB5J52_RS26395 (AB5J52_26395)	-	5825991..5826542 (+)	552	WP_369224298.1	M23 family metallopeptidase	-
AB5J52_RS26400 (AB5J52_26400)	-	5826560..5827156 (-)	597	WP_234544475.1	TetR/AcrR family transcriptional regulator	-
AB5J52_RS26405 (AB5J52_26405)	-	5827304..5828908 (+)	1605	WP_234544474.1	MDR family MFS transporter	-
AB5J52_RS26410 (AB5J52_26410)	-	5829140..5829541 (+)	402	WP_369228220.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 841 a.a.
• Molecular weight: 93014.20 Da
• Isoelectric Point: 5.8409

>NTDB_id=925441 AB5J52_RS26385 WP_234544478.1 5822099..5824624(+) (clpC) [Streptomyces sp. R39]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAAVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQVDAVKALSKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
ALAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAASGDTKTNYERMKNKVQDELKQHFRPEFLNRVDDVVVFPQLT
QEDILRIVDLMIGKVDERLKDRDMGIELSQSAKELLSKKGYDPVLGARPLRRTIQREIEDTLSEKILFGELRPGHIVVVD
TEGEGDTATFTFRGEEKSALPDVPPIEQAAGGAGPNLSKEA

Nucleotide

• Length: 2526 bp

>NTDB_id=925441 AB5J52_RS26385 WP_234544478.1 5822099..5824624(+) (clpC) [Streptomyces sp. R39]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCAAAGGCCCTGGAGAGCCTCGGCA
TTTCGCTTGAGGCGGTCCGTCAGCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGTCCGGGCACATCCCCTTC
ACCCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTGGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGTGAGGGCGAGGGCGTCGCCGCCCAGGTCCTGGTCAAGCTGGGCGCCGATCTCAACCGTG
TGCGGCAGCAGGTGATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAGACCGCCACCGCCGGCGGCCCTGCCGAGGGCACC
CCCTCGACGTCCCTGGTCCTCGACCAGTTCGGCCGGAACCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACCAAGAACAACCCGGTCCTGATCGGTGAGC
CCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTCGCCCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTGGACCTCGGTGCCCTGGTCGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTGCTCAAGGAGATCCGCACCCGCGGTGACATCATCCTGTTCATCGACGAGCTCCACACGCTGGTCGGTGCGGGTGCGG
CCGAGGGCGCCATCGACGCCGCGTCGATCCTGAAGCCGATGCTGGCCCGCGGTGAGCTGCAGACCATCGGTGCCACCACC
CTGGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTGGAGCGCCGCTTCCAGCCCATCCAGGTCGCCGAGCCGTC
CCTGCCGCACACGATCGAGATCCTCAAGGGTCTGCGTGACCGGTACGAGGCCCACCACCGGGTCTCCATCACGGACGAGG
CGCTGGTTCAGGCGGCCACCCTGGCCGACCGCTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGTTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCCGCCGT
CCGCCGGGACAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGAAGGCCGCCTCCCTCCGCGACAAGGAGAAGCAGCTCC
TGGCCGCCAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAGCTGATC
GCCGAGGTCCTCGCCACGGCCACCGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCAGCCGGCTCCTGCGCATGGA
GGACGAACTCCACAAGCGCGTCATCGGCCAGGTCGACGCCGTCAAGGCGCTGTCGAAGGCGATCCGTCGTACGCGGGCCG
GTCTGAAGGACCCGAAGCGCCCCGGTGGCTCGTTCATCTTCGCCGGTCCGTCCGGTGTCGGTAAGACCGAGCTGTCCAAG
GCCCTCGCCGAGTTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
GTCGCGTCTCTTCGGTTCGCCCCCCGGCTACGTGGGCTACGAAGAGGGCGGCCAGCTGACCGAGAAGGTCCGCCGCAAGC
CGTTCTCCGTCGTCCTCTTCGACGAGGTGGAGAAGGCCCACCCGGACATCTTCAACTCGCTGCTGCAGATCCTGGAGGAC
GGTCGCCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGCACCCG
GGACATCTCCAAGGGCTTCAACCTGGGCTTCGCGGCCTCGGGTGACACGAAGACCAACTACGAGCGCATGAAGAACAAGG
TCCAGGACGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGCGTCGACGACGTGGTCGTCTTCCCGCAGCTGACG
CAGGAGGACATCCTGCGGATCGTCGACCTGATGATCGGCAAGGTGGACGAGCGTCTGAAGGACCGGGACATGGGCATCGA
GCTCTCCCAGTCCGCCAAGGAGCTGCTGTCCAAGAAGGGCTACGACCCGGTGCTGGGCGCGCGTCCGCTGCGGCGCACGA
TCCAGCGCGAGATCGAGGACACGCTCTCGGAGAAGATCCTCTTCGGCGAGCTGCGCCCCGGTCACATCGTGGTCGTCGAC
ACGGAGGGCGAGGGCGACACCGCGACCTTCACCTTCCGCGGCGAGGAGAAGTCGGCCCTTCCCGACGTCCCGCCGATCGA
GCAGGCGGCCGGCGGAGCCGGGCCGAACCTGAGCAAGGAGGCGTAA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (209-329)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (719-799)

• AAA lid domain (AAA_lid_9) (349-449)

• AAA domain (Cdc48 subfamily) (AAA_2) (541-712)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	61.471	95.363	0.586
clpC	Streptococcus mutans UA159	44.337	98.692	0.438
clpC	Streptococcus thermophilus LMD-9	43.027	99.762	0.429
clpC	Streptococcus thermophilus LMG 18311	42.857	99.881	0.428
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.827	96.314	0.422
clpC	Streptococcus pneumoniae D39	44.209	95.482	0.422
clpC	Streptococcus pneumoniae Rx1	44.209	95.482	0.422
clpC	Streptococcus pneumoniae TIGR4	44.236	94.887	0.42
clpE	Streptococcus mutans UA159	54.313	74.435	0.404
clpE	Streptococcus pneumoniae TIGR4	52.97	74.078	0.392
clpC	Lactococcus lactis subsp. cremoris KW2	53.065	73.722	0.391
clpE	Streptococcus pneumoniae Rx1	52.809	74.078	0.391
clpE	Streptococcus pneumoniae R6	52.809	74.078	0.391
clpE	Streptococcus pneumoniae D39	52.809	74.078	0.391