Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   VKP36_RS06185 Genome accession   NZ_CP142357
Coordinates   1216347..1217384 (-) Length   345 a.a.
NCBI ID   WP_010922499.1    Uniprot ID   A0A4U9I5V9
Organism   Streptococcus pyogenes strain AW-534     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1211347..1222384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP36_RS06165 (VKP36_06165) - 1212097..1212723 (+) 627 WP_030126387.1 prepilin peptidase -
  VKP36_RS06170 (VKP36_06170) rlmN 1212805..1213884 (-) 1080 WP_030126386.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  VKP36_RS06175 (VKP36_06175) - 1213888..1214508 (-) 621 WP_002992791.1 YutD family protein -
  VKP36_RS06180 (VKP36_06180) - 1214956..1215933 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  VKP36_RS06185 (VKP36_06185) sepM 1216347..1217384 (-) 1038 WP_010922499.1 SepM family pheromone-processing serine protease Regulator
  VKP36_RS06190 (VKP36_06190) coaD 1217371..1217862 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  VKP36_RS06195 (VKP36_06195) rsmD 1217852..1218391 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  VKP36_RS06200 (VKP36_06200) asnA 1218514..1219506 (-) 993 WP_023611792.1 aspartate--ammonia ligase -
  VKP36_RS06205 (VKP36_06205) arcC 1219819..1220769 (-) 951 WP_009880962.1 carbamate kinase -
  VKP36_RS06210 (VKP36_06210) - 1220789..1222120 (-) 1332 WP_030126384.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37541.24 Da        Isoelectric Point: 9.6692

>NTDB_id=925387 VKP36_RS06185 WP_010922499.1 1216347..1217384(-) (sepM) [Streptococcus pyogenes strain AW-534]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=925387 VKP36_RS06185 WP_010922499.1 1216347..1217384(-) (sepM) [Streptococcus pyogenes strain AW-534]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGTCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGTGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9I5V9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

69.275

100

0.693