Detailed information NTG0092535

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Llc71_RS12445
• Genome accession: NZ_AP025520
• Coordinates: 2420801..2421832 (-)
• Length: 343 a.a.
• NCBI ID: WP_248536781.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain 7-1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2415801..2426832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Llc71_RS12420 (Llc71_24800)	-	2415910..2416836 (-)	927	WP_248536780.1	radical SAM protein	-
Llc71_RS12425 (Llc71_24810)	-	2416939..2417796 (-)	858	WP_046124643.1	Rgg/GadR/MutR family transcriptional regulator	-
Llc71_RS12430 (Llc71_24820)	-	2417848..2418984 (-)	1137	WP_011836074.1	MFS transporter	-
Llc71_RS12435 (Llc71_24830)	kwcM	2418981..2420300 (-)	1320	WP_046124644.1	KxxxW cyclic peptide radical SAM maturase	-
Llc71_RS12440	-	2420368..2420481 (-)	114	WP_075070627.1	KxxxW-cyclized peptide pheromone	-
Llc71_RS12445 (Llc71_24840)	sepM	2420801..2421832 (-)	1032	WP_248536781.1	SepM family pheromone-processing serine protease	Regulator
Llc71_RS12450 (Llc71_24850)	coaD	2421816..2422316 (-)	501	WP_248536782.1	pantetheine-phosphate adenylyltransferase	-
Llc71_RS12455 (Llc71_24860)	rsmD	2422364..2422903 (-)	540	WP_011836079.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Llc71_RS12460 (Llc71_24870)	-	2423076..2424293 (-)	1218	WP_011836080.1	MFS transporter	-
Llc71_RS12465 (Llc71_24880)	lmrP	2424378..2425604 (-)	1227	WP_046124646.1	multidrug efflux MFS transporter LmrP	-
Llc71_RS12470 (Llc71_24890)	-	2425843..2426286 (+)	444	WP_041931231.1	sigma-70 family RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37431.03 Da
• Isoelectric Point: 9.9181

>NTDB_id=92535 Llc71_RS12445 WP_248536781.1 2420801..2421832(-) (sepM) [Lactococcus cremoris strain 7-1]
MNKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKISNGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGMMFTLEIYSQLTGKNLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVRTIQDALTYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=92535 Llc71_RS12445 WP_248536781.1 2420801..2421832(-) (sepM) [Lactococcus cremoris strain 7-1]
ATGAACAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGCCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGGAAAATGGTCAAAGTTGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGTGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGTCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACTGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGCAGTAAACACAAGTCTACTGGAAAATATATCAAAATCTCTAATGGAAAAACCGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATGATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAAATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAGGACTATTCAGGACGCTTTAACTTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.116	100	0.484