Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   VKP54_RS05840 Genome accession   NZ_CP142356
Coordinates   1162046..1163092 (-) Length   348 a.a.
NCBI ID   WP_111711349.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain CT95-157     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1157046..1168092
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP54_RS05820 (VKP54_05820) - 1157798..1158424 (+) 627 WP_002983834.1 prepilin peptidase -
  VKP54_RS05825 (VKP54_05825) rlmN 1158506..1159585 (-) 1080 WP_031488529.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  VKP54_RS05830 (VKP54_05830) - 1159589..1160209 (-) 621 WP_002992791.1 YutD family protein -
  VKP54_RS05835 (VKP54_05835) - 1160657..1161634 (-) 978 WP_031577505.1 LacI family DNA-binding transcriptional regulator -
  VKP54_RS05840 (VKP54_05840) sepM 1162046..1163092 (-) 1047 WP_111711349.1 SepM family pheromone-processing serine protease Regulator
  VKP54_RS05845 (VKP54_05845) coaD 1163079..1163570 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  VKP54_RS05850 (VKP54_05850) rsmD 1163560..1164099 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  VKP54_RS05855 (VKP54_05855) asnA 1164222..1165214 (-) 993 WP_002983817.1 aspartate--ammonia ligase -
  VKP54_RS05860 (VKP54_05860) arcC 1165527..1166477 (-) 951 WP_010922501.1 carbamate kinase -
  VKP54_RS05865 (VKP54_05865) - 1166497..1167828 (-) 1332 WP_030126384.1 dipeptidase -

Sequence

Protein


Download         Length: 348 a.a.        Molecular weight: 37840.57 Da        Isoelectric Point: 9.7472

>NTDB_id=925333 VKP54_RS05840 WP_111711349.1 1162046..1163092(-) (sepM) [Streptococcus pyogenes strain CT95-157]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAG
LMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEA
KRAAKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1047 bp        

>NTDB_id=925333 VKP54_RS05840 WP_111711349.1 1162046..1163092(-) (sepM) [Streptococcus pyogenes strain CT95-157]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTATTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTCTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGAAAAATGGGATTGGCATTG
CCTTGACTGATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGT
CTAATGTTTACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAAC
TATTGGCAAGGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATA
TATTTTTTGTTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCC
AAACGGGCAGCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCG
CAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(129-192)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(236-312)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.678

100

0.687