Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   AB5J50_RS12980 Genome accession   NZ_CP163440
Coordinates   2791144..2794182 (-) Length   1012 a.a.
NCBI ID   WP_369257696.1    Uniprot ID   -
Organism   Streptomyces sp. R35     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2786144..2799182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB5J50_RS12955 (AB5J50_12955) - 2786983..2787405 (-) 423 WP_327427870.1 Rieske (2Fe-2S) protein -
  AB5J50_RS12960 (AB5J50_12960) - 2787583..2788641 (+) 1059 WP_369257688.1 LacI family DNA-binding transcriptional regulator -
  AB5J50_RS12965 (AB5J50_12965) - 2788638..2789549 (+) 912 WP_369257690.1 carbohydrate kinase -
  AB5J50_RS12970 (AB5J50_12970) - 2789558..2790412 (-) 855 WP_369257692.1 helix-turn-helix domain-containing protein -
  AB5J50_RS12975 (AB5J50_12975) - 2790513..2791082 (+) 570 WP_369257694.1 YceI family protein -
  AB5J50_RS12980 (AB5J50_12980) uvrA 2791144..2794182 (-) 3039 WP_369257696.1 excinuclease ABC subunit UvrA Machinery gene
  AB5J50_RS12985 (AB5J50_12985) - 2794406..2795095 (+) 690 WP_327427876.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  AB5J50_RS12990 (AB5J50_12990) - 2795105..2795761 (+) 657 WP_369257698.1 MBL fold metallo-hydrolase -
  AB5J50_RS12995 (AB5J50_12995) - 2796317..2797201 (+) 885 WP_369257700.1 ABC transporter substrate-binding protein -
  AB5J50_RS13000 (AB5J50_13000) - 2797198..2798109 (+) 912 WP_369257702.1 amino acid ABC transporter permease -
  AB5J50_RS13005 (AB5J50_13005) - 2798106..2798873 (+) 768 WP_369257704.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 1012 a.a.        Molecular weight: 111220.41 Da        Isoelectric Point: 7.4666

>NTDB_id=925327 AB5J50_RS12980 WP_369257696.1 2791144..2794182(-) (uvrA) [Streptomyces sp. R35]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPITRQSPQAIVDKVLELPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGETIQLTEPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPECTGIGTRMEVDPELIVPDEEKSLDEGAIHPWSHGHTK
DYFGRLVGALADALGFRTDIPFAGLPQRAKKALLYGHKTQIEVRYRNRYGRERVYTTPFEGAVPFVKRRHSESESDASRE
RFEGYMREVPCPTCEGTRLKPLVLAVTVMEKSIAEVSGMSISDCADFLGELRLNARDKKIAERVLKEVNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WIVDIGPGAGEHGGKVVHSGSLKELLVNEESQTGQYLSGKKSIPLPDIRRPRDPSRQLTVHGARENNLQDIDVSFPLGIL
TAVTGVSGSGKSTLVNDILYTHLARELNGARSVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLFA
ETTEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSVADVLNMPIEEA
MHFFEAVPAIARHLNTLNDVGLGYVRLGQSATTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLLTVLS
GLVDKGNTVIVIEHNLDVIKTADWLVDMGPEGGAGGGLVIAEGTPEEVAGVPASHTGKFLREVLSADRISDAAPVKAVRK
TAAKKTVAARATAKKTTTKTVNNTATKKAAAATKKTATKKATPAKTTRARKA

Nucleotide


Download         Length: 3039 bp        

>NTDB_id=925327 AB5J50_RS12980 WP_369257696.1 2791144..2794182(-) (uvrA) [Streptomyces sp. R35]
GTGGCCGACCGTCTCATCGTCCGTGGAGCGCGCGAGCACAATCTCAAGAATGTCTCGCTCGACCTCCCGCGCGACTCGCT
CATCGTCTTCACGGGCTTGTCGGGGTCGGGCAAGTCCTCGCTGGCCTTCGACACCATCTTCGCCGAGGGGCAGCGGCGCT
ACGTGGAGTCGCTCTCCTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTGGACTTCATCGAAGGCCTC
TCCCCGGCGGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACCATCACCGAGGTCTACGA
CTATCTGCGCCTGCTCTTCGCGCGCATCGGCAAGCCGCACTGTCCCGAGTGCGGCCGCCCCATCACGCGCCAGTCGCCGC
AGGCCATCGTCGACAAGGTCCTGGAGCTGCCGGAGGGGAGCCGCTTCCAGGTCCTGTCGCCGCTGGTGCGCGAGCGCAAG
GGAGAGTTCGTCGACCTCTTCGCCGATCTCCAGACCAAGGGGTACAGCAGGGCCCGGGTCGACGGCGAGACGATCCAGCT
CACCGAGCCGCCCACGCTCAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGCCTCACGGTGAAGGACTCGG
CCAAGCGCCGCCTCACCGACTCCGTGGAGACCGCCCTCGGCCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGCATGTACTCGGAGCACCTGTACTGCCCGTACGACGACCTGTCCTTCGAAGAGCT
GGAGCCCCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCCGAGTGCACCGGTATCGGTACGCGCATGGAGGTCG
ACCCGGAGCTGATCGTCCCGGACGAGGAGAAGTCGCTCGACGAGGGCGCCATCCACCCCTGGTCGCACGGGCACACCAAG
GACTACTTCGGGCGGCTCGTCGGAGCCCTCGCCGACGCGTTGGGATTCCGAACCGACATCCCCTTCGCCGGTCTTCCGCA
ACGTGCCAAGAAGGCCCTGCTCTACGGGCACAAGACGCAGATCGAGGTCCGCTACCGAAACCGGTACGGACGCGAGCGCG
TGTACACCACGCCCTTCGAAGGGGCCGTCCCCTTCGTCAAACGGCGGCACAGCGAGTCCGAGAGCGACGCGAGCCGCGAG
CGCTTCGAGGGCTATATGCGCGAGGTGCCCTGCCCCACCTGTGAGGGCACGCGCCTGAAGCCGCTCGTCCTCGCGGTCAC
GGTCATGGAGAAGTCGATCGCCGAGGTCTCCGGGATGTCCATCAGCGACTGCGCGGACTTCCTGGGCGAGCTGAGGCTCA
ACGCCCGAGACAAGAAGATCGCCGAGCGCGTCCTGAAGGAGGTCAACGAACGGCTGCGCTTCCTGGTCGACGTCGGCCTC
GACTACCTGTCGCTGAACCGCGCGGCCGGTACCCTCTCCGGCGGTGAGGCCCAGCGCATCCGGCTGGCCACCCAGATCGG
CTCCGGACTCGTGGGCGTCCTGTACGTCCTCGACGAGCCCTCCATCGGTCTGCACCAGCGCGACAACCACCGACTGATCG
AGACCCTGGTCCGGCTGCGCGACATGGGCAACACGCTCATCGTGGTGGAGCACGACGAGGACACCATCAAGGTCGCCGAC
TGGATCGTCGACATCGGCCCCGGCGCGGGCGAGCACGGCGGCAAGGTCGTGCACAGCGGCTCCCTGAAGGAGCTGCTCGT
CAACGAGGAGTCGCAGACCGGCCAGTACCTGTCGGGCAAGAAGTCCATCCCGCTGCCCGACATCCGCCGCCCCCGGGACC
CGTCCCGGCAGCTCACGGTGCACGGCGCCCGGGAGAACAACCTCCAGGACATCGACGTGTCCTTCCCGCTGGGCATCCTC
ACGGCCGTCACGGGCGTGTCGGGCTCCGGCAAGTCGACGCTGGTCAACGACATCCTGTACACGCACCTGGCCCGAGAGCT
GAACGGCGCGAGAAGCGTCCCCGGCCGGCACACGCGCGTGGACGGCGACGACCTCGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCCATCGGCCGAACCCCCCGGTCCAACCCGGCCACGTACACCGGAGTCTTCGACCACGTCCGCAAGCTGTTCGCG
GAGACGACCGAGGCGAAGGTCCGCGGCTATCTGCCCGGGCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAACTG
CTCCGGCGACGGCACCATCAAGATCGAGATGAACTTCCTCCCGGACGTGTACGTCCCGTGCGAGGTCTGCCACGGTGCGC
GCTACAACCGGGAGACCCTGGAGGTCCACTACAAGGGCAAGTCCGTCGCCGACGTCCTGAACATGCCGATCGAGGAAGCC
ATGCACTTCTTCGAGGCCGTCCCGGCGATCGCCCGCCACCTCAACACGCTGAACGACGTCGGTCTCGGCTACGTCCGGCT
CGGTCAGTCCGCGACCACCCTGTCCGGCGGCGAGGCCCAGCGTGTGAAGCTCGCCAGCGAACTGCAGAAGCGGTCCACCG
GACGCACGGTCTACGTCCTCGACGAGCCGACCACCGGCCTTCACTTCGAGGACATCAGCAAGCTCCTCACCGTGCTCTCC
GGACTGGTCGACAAGGGCAACACGGTCATCGTCATCGAGCACAACCTGGACGTCATCAAGACCGCCGACTGGCTCGTCGA
CATGGGCCCCGAGGGCGGCGCGGGCGGCGGTCTCGTGATCGCCGAGGGCACGCCGGAGGAGGTCGCCGGCGTTCCGGCCA
GCCACACCGGAAAGTTCCTGCGCGAGGTCCTCAGCGCCGACCGGATCAGCGACGCCGCCCCGGTGAAGGCCGTGCGCAAG
ACCGCCGCCAAGAAGACGGTGGCGGCCAGGGCGACGGCGAAGAAGACGACCACGAAGACCGTCAACAACACGGCCACGAA
GAAGGCGGCCGCGGCCACGAAGAAGACGGCCACCAAGAAGGCGACCCCCGCGAAGACCACGCGGGCTCGCAAGGCCTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

ABC transporter (ABC_tran)

(628-864)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.46

93.379

0.537
  uvrA Streptococcus pneumoniae TIGR4

57.46

93.379

0.537
  uvrA Streptococcus pneumoniae D39

57.46

93.379

0.537