Detailed information NTG0925326

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: VKP54_RS04390
• Genome accession: NZ_CP142356
• Coordinates: 865928..866764 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain CT95-157
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 860928..871764

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP54_RS04360 (VKP54_04360)	-	861413..861850 (+)	438	WP_031488279.1	hypothetical protein	-
VKP54_RS04365 (VKP54_04365)	-	861900..862811 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
VKP54_RS04370 (VKP54_04370)	trhA	862928..863578 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
VKP54_RS04375 (VKP54_04375)	-	863575..864015 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
VKP54_RS04380 (VKP54_04380)	ylqF	864234..865082 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
VKP54_RS04385 (VKP54_04385)	-	865072..865863 (+)	792	WP_031488275.1	ribonuclease HII	-
VKP54_RS04390 (VKP54_04390)	dprA	865928..866764 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
VKP54_RS04395 (VKP54_04395)	topA	866871..869000 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
VKP54_RS04400 (VKP54_04400)	-	869075..869932 (-)	858	Protein_826	LysR family transcriptional regulator	-
VKP54_RS04405 (VKP54_04405)	-	869972..870517 (+)	546	Protein_827	PTS sugar transporter subunit IIC	-
VKP54_RS04410 (VKP54_04410)	-	870532..871524 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=925326 VKP54_RS04390 WP_031488274.1 865928..866764(+) (dprA) [Streptococcus pyogenes strain CT95-157]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=925326 VKP54_RS04390 WP_031488274.1 865928..866764(+) (dprA) [Streptococcus pyogenes strain CT95-157]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363