Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   VKP53_RS03095 Genome accession   NZ_CP142354
Coordinates   605188..606225 (+) Length   345 a.a.
NCBI ID   WP_002983824.1    Uniprot ID   A0A4U9C0Q7
Organism   Streptococcus pyogenes strain 6745-99     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 600188..611225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP53_RS03070 (VKP53_03070) - 600452..601783 (+) 1332 WP_115230460.1 dipeptidase -
  VKP53_RS03075 (VKP53_03075) arcC 601803..602753 (+) 951 WP_010922501.1 carbamate kinase -
  VKP53_RS03080 (VKP53_03080) asnA 603066..604058 (+) 993 WP_023611792.1 aspartate--ammonia ligase -
  VKP53_RS03085 (VKP53_03085) rsmD 604181..604720 (+) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  VKP53_RS03090 (VKP53_03090) coaD 604710..605201 (+) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  VKP53_RS03095 (VKP53_03095) sepM 605188..606225 (+) 1038 WP_002983824.1 SepM family pheromone-processing serine protease Regulator
  VKP53_RS03100 (VKP53_03100) - 606639..607615 (+) 977 Protein_550 LacI family DNA-binding transcriptional regulator -
  VKP53_RS03105 (VKP53_03105) - 608063..608683 (+) 621 WP_002992791.1 YutD family protein -
  VKP53_RS03110 (VKP53_03110) rlmN 608687..609766 (+) 1080 WP_326675046.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  VKP53_RS03115 (VKP53_03115) - 609848..610474 (-) 627 WP_111704576.1 prepilin peptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37555.27 Da        Isoelectric Point: 9.6692

>NTDB_id=925214 VKP53_RS03095 WP_002983824.1 605188..606225(+) (sepM) [Streptococcus pyogenes strain 6745-99]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=925214 VKP53_RS03095 WP_002983824.1 605188..606225(+) (sepM) [Streptococcus pyogenes strain 6745-99]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9C0Q7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69