Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   AB5J48_RS07405 Genome accession   NZ_CP163433
Coordinates   1708933..1711941 (-) Length   1002 a.a.
NCBI ID   WP_031018530.1    Uniprot ID   -
Organism   Streptomyces sp. R17     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1703933..1716941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB5J48_RS07385 (AB5J48_07385) - 1705164..1706111 (+) 948 WP_369150027.1 hypothetical protein -
  AB5J48_RS07390 (AB5J48_07390) - 1706170..1706589 (-) 420 WP_006135281.1 Rieske (2Fe-2S) protein -
  AB5J48_RS07395 (AB5J48_07395) - 1706896..1707948 (+) 1053 WP_203349856.1 LacI family DNA-binding transcriptional regulator -
  AB5J48_RS07400 (AB5J48_07400) - 1707945..1708865 (+) 921 WP_031018531.1 carbohydrate kinase -
  AB5J48_RS07405 (AB5J48_07405) uvrA 1708933..1711941 (-) 3009 WP_031018530.1 excinuclease ABC subunit UvrA Machinery gene
  AB5J48_RS07410 (AB5J48_07410) - 1712165..1712854 (+) 690 WP_086684457.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  AB5J48_RS07415 (AB5J48_07415) - 1712894..1713550 (+) 657 WP_006135286.1 MBL fold metallo-hydrolase -
  AB5J48_RS07420 (AB5J48_07420) - 1713578..1714774 (-) 1197 WP_228679176.1 amidohydrolase family protein -
  AB5J48_RS07425 (AB5J48_07425) - 1714876..1715637 (-) 762 WP_031018524.1 class I SAM-dependent methyltransferase -
  AB5J48_RS07430 (AB5J48_07430) aroQ 1715776..1716249 (-) 474 WP_006135289.1 type II 3-dehydroquinate dehydratase -

Sequence

Protein


Download         Length: 1002 a.a.        Molecular weight: 110177.09 Da        Isoelectric Point: 7.9905

>NTDB_id=925076 AB5J48_RS07405 WP_031018530.1 1708933..1711941(-) (uvrA) [Streptomyces sp. R17]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPISRQSPQAIVDKVLELPEGSRFQVLSPLVRERK
GEFVDLFSDLQTKGYSRARVDGETIQLSTPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPECTGIGTRMEVDPELIVPDPDKSLDEGAIHPWSHGHTK
DYFDRLVGALADALGFRTDIPWAGLPQRARKALLHGHKTQVEVRYRNRYGRERRYTTAFEGAVPFVKRRHSEAESDASRE
RFEGYMREVPCPSCEGTRLKPVVLAVTVMGKSIAEVSAMSISDCADFLGELKLTARDKKIAERVLKEVNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WIVDIGPGAGEHGGKVVHSGSLKELLANAESQTGQYLSGKKAIPLPEMRRPHDPSRRLTVRGARENNLRDIDVSFPLGVF
TAVTGVSGSGKSTLVNDILYTHLARELNGARNVPGRHTRVEGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHIRRLFA
ETTEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLDVHYKGKSIADVLNMPIEEA
MHFFEAVPAISRHLRTLNDVGLGYVRLGQSATTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLLTVLS
GLVDKGNTVIVIEHNLDVVKTADWVVDMGPEGGSGGGLVVAEGTPEQVAGVPASHTGKFLREILGAERISDASQVRAPRK
AAKKTVAARSTAKKTTSKTVGTTAKKTAGKTAATRTTRGTKA

Nucleotide


Download         Length: 3009 bp        

>NTDB_id=925076 AB5J48_RS07405 WP_031018530.1 1708933..1711941(-) (uvrA) [Streptomyces sp. R17]
GTGGCCGACCGTCTCATCGTCCGTGGAGCGCGCGAGCACAACCTCAAGAACGTCTCGCTCGACCTCCCGCGCGACTCGCT
CATCGTCTTCACGGGCCTGTCGGGGTCGGGCAAGTCCTCGCTGGCCTTCGACACCATCTTCGCCGAGGGGCAGCGGCGCT
ACGTCGAGTCCCTCTCCTCCTACGCCCGCCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAGGGCCTG
TCCCCGGCGGTCTCCATCGACCAGAAGTCCACCTCGCGCAACCCGCGTTCCACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTGCGCCTGCTCTTCGCGCGCATCGGCAAGCCGCACTGTCCCGAGTGCGGCCGGCCCATCTCGCGCCAGTCGCCGC
AGGCCATCGTCGACAAGGTCCTGGAGCTTCCGGAGGGGAGCCGCTTCCAGGTGCTCTCCCCGCTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCTCCGACCTCCAGACCAAGGGCTACTCCCGCGCGCGCGTGGACGGCGAGACGATCCAGCT
CTCCACCCCGCCCACGCTGAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGCCTCACGGTGAAGGACAGCG
CCAAGCGCCGTCTCACCGACTCCGTGGAGACCGCCCTCGGCCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGCATGTACTCCGAGCACCTCTACTGCCCCTACGACGACCTGTCGTTCGAGGAGCT
GGAGCCCCGCTCGTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCCGAGTGCACCGGCATCGGCACGCGCATGGAGGTCG
ACCCCGAGCTGATCGTCCCCGACCCGGACAAGAGCCTCGACGAGGGCGCCATCCACCCGTGGTCCCACGGCCACACCAAG
GACTACTTCGACCGCCTCGTCGGCGCCCTCGCGGACGCGCTCGGCTTCCGCACGGACATCCCGTGGGCCGGCCTGCCGCA
GCGCGCCAGGAAGGCCCTGCTGCACGGTCACAAGACCCAGGTCGAGGTCCGCTACCGCAACCGCTACGGGCGCGAGCGCC
GGTACACCACGGCCTTCGAGGGCGCGGTGCCGTTCGTCAAGCGGCGGCACAGCGAGGCCGAGAGCGACGCCAGCCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCTCCTGCGAGGGCACGCGCCTCAAGCCGGTCGTCCTCGCCGTCAC
GGTCATGGGCAAGTCCATCGCCGAGGTCTCCGCCATGTCCATCAGCGACTGCGCGGACTTCCTGGGCGAGCTCAAGCTGA
CCGCCCGCGACAAGAAGATCGCCGAGCGCGTCCTCAAGGAGGTCAACGAGCGGCTGCGCTTCCTCGTCGACGTCGGCCTC
GACTACCTCTCGCTGAACCGCGCGGCGGGCACCCTCTCCGGCGGCGAGGCCCAGCGCATCCGCCTGGCCACCCAGATCGG
CAGCGGCCTCGTCGGCGTGCTCTACGTGCTCGACGAGCCCTCCATCGGCCTGCACCAGCGGGACAACCACCGGCTGATCG
AGACCCTGGTCCGGCTGCGCGACATGGGCAACACGCTCATCGTCGTGGAGCACGACGAGGACACCATCAAGGTCGCCGAC
TGGATCGTCGACATCGGCCCCGGCGCCGGCGAGCACGGCGGCAAGGTCGTGCACAGCGGCTCCCTCAAGGAGCTGCTCGC
CAACGCCGAGTCGCAGACCGGCCAGTACCTGTCGGGCAAGAAGGCGATCCCGCTGCCCGAGATGCGGCGCCCGCACGACC
CGTCGCGCCGCCTCACGGTGCGCGGCGCCCGTGAGAACAACCTGCGGGACATCGACGTGTCCTTCCCGCTGGGCGTCTTC
ACCGCGGTCACCGGCGTCTCCGGATCCGGCAAGTCCACGCTGGTCAACGACATCCTGTACACGCACCTCGCCCGGGAGCT
GAACGGCGCGCGCAACGTGCCCGGCCGGCACACCCGCGTCGAGGGCGACGACCTCGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCCATCGGCCGCACCCCGCGGTCCAACCCGGCGACGTACACGGGCGTCTTCGACCACATCCGCAGGCTCTTCGCG
GAGACGACGGAGGCGAAGGTCCGCGGCTACCTGCCGGGCCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAACTG
CTCCGGCGACGGCACCATCAAGATCGAGATGAACTTCCTGCCGGACGTCTACGTCCCCTGCGAGGTCTGCCACGGCGCCC
GCTACAACCGGGAGACGCTGGACGTCCACTACAAGGGCAAGTCCATCGCCGACGTGCTGAACATGCCGATCGAAGAGGCC
ATGCACTTCTTCGAGGCGGTCCCGGCGATCTCCCGCCACCTCAGGACGCTCAACGACGTCGGCCTCGGCTACGTCCGGCT
CGGCCAGTCCGCGACCACCCTGTCCGGCGGCGAGGCGCAGCGCGTCAAGCTCGCCAGCGAACTGCAGAAGCGCTCCACCG
GCCGCACGGTCTACGTCCTCGACGAGCCGACGACCGGCCTGCACTTCGAGGACATCAGCAAGCTGCTGACGGTCCTGTCC
GGCCTGGTCGACAAGGGCAACACCGTGATCGTCATCGAGCACAACCTCGATGTCGTCAAGACGGCCGACTGGGTCGTCGA
CATGGGCCCCGAGGGCGGCTCCGGCGGCGGCCTCGTCGTCGCGGAGGGCACGCCCGAGCAGGTCGCCGGGGTGCCGGCCA
GCCACACCGGCAAGTTCCTGCGGGAGATCCTGGGCGCGGAGCGGATCAGCGACGCCTCGCAGGTCCGCGCCCCGCGCAAG
GCGGCCAAGAAGACGGTCGCCGCCCGGTCGACGGCGAAGAAGACCACGAGCAAGACGGTCGGGACCACCGCCAAGAAGAC
GGCCGGGAAGACCGCCGCGACCAGGACGACGCGCGGCACCAAGGCCTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

ABC transporter (ABC_tran)

(628-864)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.72

94.311

0.535
  uvrA Streptococcus pneumoniae TIGR4

56.72

94.311

0.535
  uvrA Streptococcus pneumoniae D39

56.72

94.311

0.535