Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   VKP55_RS05795 Genome accession   NZ_CP142351
Coordinates   1148576..1150858 (+) Length   760 a.a.
NCBI ID   WP_011054709.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SS1366     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1143576..1155858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP55_RS05775 (VKP55_05775) - 1144943..1146352 (-) 1410 WP_002993337.1 cryptochrome/photolyase family protein -
  VKP55_RS05780 (VKP55_05780) - 1146501..1147235 (-) 735 WP_009880900.1 amino acid ABC transporter ATP-binding protein -
  VKP55_RS05785 (VKP55_05785) - 1147235..1147921 (-) 687 WP_011054708.1 amino acid ABC transporter permease -
  VKP55_RS05790 (VKP55_05790) - 1148048..1148278 (-) 231 WP_002983885.1 YkuJ family protein -
  VKP55_RS05795 (VKP55_05795) clpE 1148576..1150858 (+) 2283 WP_011054709.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  VKP55_RS05800 (VKP55_05800) - 1150986..1151441 (+) 456 WP_002989103.1 NUDIX hydrolase -
  VKP55_RS05805 (VKP55_05805) - 1151492..1151794 (+) 303 WP_326673916.1 DUF1827 family protein -
  VKP55_RS05810 (VKP55_05810) ileS 1152059..1154860 (-) 2802 WP_109828822.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 760 a.a.        Molecular weight: 84717.89 Da        Isoelectric Point: 5.0552

>NTDB_id=925057 VKP55_RS05795 WP_011054709.1 1148576..1150858(+) (clpE) [Streptococcus pyogenes strain SS1366]
MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSILNGLTPGYRAQNRSTSPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRYGGNYNGQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
ITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKQLRALMTNSENITIKAVKEGDSFLNEESLD

Nucleotide


Download         Length: 2283 bp        

>NTDB_id=925057 VKP55_RS05795 WP_011054709.1 1148576..1150858(+) (clpE) [Streptococcus pyogenes strain SS1366]
ATGCTGTGTCAAAATTGTAATTTAAACGAATCTACTATTCATCTTTATACAAGTGTTAATGGAAAACAAAGACAGGTTGA
TCTCTGTCAAAATTGTTATCAAATCATGAAATCCGATCCTGCCAATTCTATTTTAAATGGCCTAACCCCAGGATATAGAG
CACAAAATAGATCCACAAGTCCTTTCTTTGATGACTTTTTTGGTGATTTGAATAATTTTAGAGCTTTTGGTAATCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGCGGAGGACGCTATGGTGGTAACTACAACGGACAACGACCTGC
TCAGCCACAAACACCAAATCAGCAAGCAAAGGGCTTATTAGAAGAGTTTGGGATTAATGTCACAGATATTGCAAGAAATG
GTAATATTGATCCTGTTATTGGTCGTGACGAAGAGATTACACGCGTTATCGAGATCCTCAACCGCCGTACTAAAAATAAT
CCTGTGCTAATTGGTGAGCCTGGAGTTGGTAAAACTGCTGTTGTAGAAGGTTTGGCTCAAAAAATTATTGATGGTACTGT
TCCTCAAAAACTCCAAGGCAAGCAAGTGATTCGTCTTGATGTGGTTAGCCTCGTTCAGGGAACAGGTATCCGTGGTCAGT
TTGAAGAGCGCATGCAAAAATTAATGGAAGAAATCCGCAATCGCAAGGATGTGATTCTCTTTATTGATGAAATTCATGAG
ATTGTCGGTGCTGGTTCTGCAGGAGACGGCAATATGGATGCTGGTAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACATTAAATGAATACCGTATTATTGAAAAAGACGCTGCCTTAGAACGACGTATGCAACCCG
TTAAAGTTGATGAACCTTCTGTTGAGGAAACCATCACGATTTTAAAAGGTATCCAACCGAAATACGAAGACTATCATCAT
GTCAAATATAGCCCAGCCGCTATTGAAGCTGCCGCTCATTTATCTAACCGCTATATTCAAGACCGTTTTCTTCCTGATAA
GGCTATTGATCTTCTGGACGAAGCTGGTTCCAAAATGAATCTAACCCTCAACTTTGTTGATCCTAAAGAAATTGACAAAC
GTCTTATTGAAGCTGAGAATCTCAAGGCGCAAGCTACTCGAGACGAAGACTATGAACGCGCAGCTTATTTCCGCGATCAA
ATTACAAAATACAAAGAAATGCAGGCTCAAAAAGTCGATGAGCAAGATATTCCCATCATTACTGAAAAAACCATTGAAGC
TATTGTAGAGCAAAAAACTAATATTCCAGTTGGGGACTTAAAAGAAAAGGAACAGTCTCAACTCGTAAACTTAGCCAATG
ATCTGAAAGCACACGTGATCGGGCAAGACGATGCTGTTGATAAAATCGCTAAGGCTATTCGTCGTAACCGTGTGGGATTA
GGAACTCCAAATCGCCCTATTGGTTCTTTCTTATTCGTTGGACCGACTGGGGTTGGTAAAACTGAATTGTCTAAACAACT
AGCCATTGAACTCTTTGGTTCGACAAACAATATGATTCGCTTTGACATGTCCGAATACATGGAAAAACACGCTGTCGCCA
AATTAGTCGGGGCTCCTCCAGGTTATGTCGGCTATGAAGAAGCTGGACAGCTAACCGAACAAGTTCGTCGCAATCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAAGCCCATCCTGACGTCATGCACATGTTCTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGAACAGTCAGCTTCAAGGACACCATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GCGAAGCTTCTGTCGGATTTGGTGCTGCTAGAGAAGGACGGACAAGTTCTGTCCTTGGTGAATTAAGCAACTTCTTCAGC
CCAGAGTTTATGAATCGTTTCGATGGTATTATTGAATTCAAAGCTTTATCTAAAGAGCATTTGCTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATGAGCGCTTAGGCTATAATGGGATTCATCTTGATGTGACACAAAAGGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGCGCTCGGCCGCTCCGTCGTACTATCCAAGATTATATAGAAGATGCCATTACA
GACTATTATTTAGAGCACCCAACTGAAAAACAGTTACGTGCACTGATGACAAACAGTGAAAATATCACGATTAAAGCTGT
TAAAGAGGGAGATTCTTTTCTTAACGAAGAGTCTCTCGATTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(300-397)

ATPase family associated with various cellular activities (AAA) (AAA)

(162-281)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(656-729)

AAA domain (Cdc48 subfamily) (AAA_2)

(485-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.759

98.421

0.834
  clpE Streptococcus pneumoniae Rx1

82.823

98.816

0.818
  clpE Streptococcus pneumoniae D39

82.823

98.816

0.818
  clpE Streptococcus pneumoniae R6

82.823

98.816

0.818
  clpE Streptococcus pneumoniae TIGR4

82.69

98.816

0.817
  clpC Lactococcus lactis subsp. cremoris KW2

75.164

100

0.753
  clpC Bacillus subtilis subsp. subtilis str. 168

51.593

86.711

0.447
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46

85.526

0.393
  clpC Streptococcus pneumoniae Rx1

47.84

82.237

0.393
  clpC Streptococcus pneumoniae D39

47.84

82.237

0.393
  clpC Streptococcus pneumoniae TIGR4

47.84

82.237

0.393
  clpC Streptococcus mutans UA159

47.573

81.316

0.387
  clpC Streptococcus thermophilus LMD-9

47.115

82.105

0.387
  clpC Streptococcus thermophilus LMG 18311

46.795

82.105

0.384