Detailed information NTG0924940

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: VKP35_RS03160
• Genome accession: NZ_CP142349
• Coordinates: 618204..620486 (-)
• Length: 760 a.a.
• NCBI ID: WP_326623225.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 11RS100
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 613204..625486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP35_RS03145 (VKP35_03145)	ileS	614202..617003 (+)	2802	WP_326623222.1	isoleucine--tRNA ligase	-
VKP35_RS03150 (VKP35_03150)	-	617268..617570 (-)	303	WP_002983878.1	DUF1827 family protein	-
VKP35_RS03155 (VKP35_03155)	-	617621..618076 (-)	456	WP_002983880.1	NUDIX hydrolase	-
VKP35_RS03160 (VKP35_03160)	clpE	618204..620486 (-)	2283	WP_326623225.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VKP35_RS03165 (VKP35_03165)	-	620783..621013 (+)	231	WP_002983885.1	YkuJ family protein	-
VKP35_RS03170 (VKP35_03170)	-	621140..621826 (+)	687	WP_111713319.1	amino acid ABC transporter permease	-
VKP35_RS03175 (VKP35_03175)	-	621826..622560 (+)	735	WP_002983889.1	amino acid ABC transporter ATP-binding protein	-
VKP35_RS03180 (VKP35_03180)	-	622708..624117 (+)	1410	WP_002983891.1	cryptochrome/photolyase family protein	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 84704.85 Da
• Isoelectric Point: 5.0123

>NTDB_id=924940 VKP35_RS03160 WP_326623225.1 618204..620486(-) (clpE) [Streptococcus pyogenes strain 11RS100]
MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSILNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRYGGNYNGQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
ITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGVHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKQLRALMTNSENITIKAVKEGDSFLNEESLD

Nucleotide

• Length: 2283 bp

>NTDB_id=924940 VKP35_RS03160 WP_326623225.1 618204..620486(-) (clpE) [Streptococcus pyogenes strain 11RS100]
ATGCTGTGTCAAAATTGTAATTTAAACGAATCTACTATTCATCTTTATACAAGTGTTAATGGAAAACAAAGACAGGTTGA
TCTCTGTCAAAATTGTTATCAAATCATGAAATCCGATCCTGCCAATTCTATTTTAAATGGCCTAACCCCAGGATATAGAG
CACAAGATAGATCCACAAGTCCTTTCTTTGATGACTTTTTTGGTGATTTGAATAATTTTAGAGCTTTTGGTAATCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGCGGAGGACGCTATGGTGGTAACTACAACGGACAACGACCTGC
TCAGCCACAAACACCAAATCAGCAAGCAAAGGGCTTATTAGAAGAGTTTGGGATTAATGTCACAGATATTGCAAGAAATG
GTAATATTGATCCTGTTATTGGTCGTGACGAAGAGATTACACGCGTTATCGAGATCCTCAACCGCCGTACTAAAAATAAT
CCTGTGCTAATTGGTGAGCCTGGAGTTGGTAAAACTGCTGTTGTAGAAGGTTTGGCTCAAAAAATTATTGATGGTACTGT
TCCTCAAAAACTCCAAGGCAAGCAAGTGATTCGTCTTGATGTGGTTAGCCTCGTTCAGGGAACAGGTATCCGTGGTCAGT
TTGAAGAGCGCATGCAAAAATTAATGGAAGAAATTCGCAATCGCAAGGATGTGATTCTCTTTATTGATGAAATTCATGAG
ATTGTCGGTGCTGGTTCTGCAGGAGACGGCAATATGGATGCTGGTAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACATTAAATGAATACCGTATTATTGAAAAAGACGCTGCCTTAGAACGACGTATGCAACCCG
TTAAAGTTGATGAACCTTCTGTTGAGGAAACCATCACGATTTTAAAAGGTATCCAACCGAAATACGAAGACTATCATCAT
GTCAAATATAGCCCAGCCGCTATTGAAGCTGCCGCTCATTTATCTAACCGCTATATTCAAGACCGTTTTCTTCCTGATAA
GGCTATTGATCTTCTGGACGAAGCTGGTTCCAAAATGAATCTAACCCTCAACTTTGTTGATCCTAAAGAAATTGACAAAC
GTCTTATTGAAGCTGAGAATCTCAAGGCGCAAGCTACTCGAGACGAAGACTATGAACGCGCAGCTTATTTCCGCGATCAA
ATTACAAAATACAAAGAAATGCAGGCTCAAAAAGTCGATGAGCAAGATATTCCCATCATTACTGAAAAAACCATTGAAGC
TATTGTAGAGCAAAAAACTAATATTCCAGTTGGGGACTTAAAAGAAAAGGAACAGTCTCAACTCGTAAACTTAGCCAATG
ATCTGAAAGCACACGTGATCGGGCAAGACGATGCTGTTGATAAAATCGCTAAGGCTATTCGTCGTAACCGTGTGGGATTA
GGAACTCCAAATCGCCCTATTGGTTCTTTCTTATTCGTTGGACCGACTGGGGTTGGTAAAACTGAATTGTCTAAACAACT
AGCCATTGAACTCTTTGGTTCGACAAACAATATGATTCGCTTTGACATGTCCGAATACATGGAAAAACACGCTGTCGCCA
AATTAGTCGGGGCTCCTCCAGGTTATGTCGGCTATGAAGAAGCTGGACAGCTAACCGAACAAGTTCGTCGCAATCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAAGCCCATCCTGACGTCATGCACATGTTCTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGAACAGTCAGCTTCAAGGACACCATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GCGAAGCTTCTGTCGGATTTGGTGCTGCTAGAGAAGGACGGACAAGTTCTGTCCTTGGTGAATTAAGCAACTTCTTCAGC
CCAGAGTTTATGAATCGTTTCGATGGTATTATTGAATTCAAAGCTTTATCTAAAGAGCATTTGCTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATGAGCGCTTAGGCTATAATGGGGTTCATCTTGATGTGACACAAAAGGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGCGCTCGGCCGCTCCGTCGTACTATCCAAGATTATATAGAAGATGCCATTACA
GACTATTATTTAGAACACCCAACTGAAAAACAGTTACGTGCACTGATGACAAACAGTGAAAATATCACGATTAAAGCTGT
TAAAGAGGGAGATTCTTTTCTTAACGAAGAGTCTCTCGATTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (300-397)

• ATPase family associated with various cellular activities (AAA) (AAA) (162-281)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (656-729)

• AAA domain (Cdc48 subfamily) (AAA_2) (485-648)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.626	98.421	0.833
clpE	Streptococcus pneumoniae Rx1	82.557	98.816	0.816
clpE	Streptococcus pneumoniae D39	82.557	98.816	0.816
clpE	Streptococcus pneumoniae R6	82.557	98.816	0.816
clpE	Streptococcus pneumoniae TIGR4	82.423	98.816	0.814
clpC	Lactococcus lactis subsp. cremoris KW2	75.033	100	0.751
clpC	Bacillus subtilis subsp. subtilis str. 168	51.593	86.711	0.447
clpC	Streptococcus pneumoniae D39	47.68	82.237	0.392
clpC	Streptococcus pneumoniae Rx1	47.68	82.237	0.392
clpC	Streptococcus pneumoniae TIGR4	47.68	82.237	0.392
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.846	85.526	0.392
clpC	Streptococcus mutans UA159	47.411	81.316	0.386
clpC	Streptococcus thermophilus LMD-9	46.955	82.105	0.386
clpC	Streptococcus thermophilus LMG 18311	46.635	82.105	0.383