Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   AB5J58_RS09525 Genome accession   NZ_CP163431
Coordinates   2044999..2047995 (+) Length   998 a.a.
NCBI ID   WP_369187180.1    Uniprot ID   -
Organism   Streptomyces sp. R08     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2039999..2052995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB5J58_RS09500 (AB5J58_09500) - 2040389..2041150 (-) 762 WP_369187176.1 amino acid ABC transporter ATP-binding protein -
  AB5J58_RS09505 (AB5J58_09505) - 2041147..2042064 (-) 918 WP_266767553.1 amino acid ABC transporter permease -
  AB5J58_RS09510 (AB5J58_09510) - 2042061..2042945 (-) 885 WP_369187177.1 ABC transporter substrate-binding protein -
  AB5J58_RS09515 (AB5J58_09515) - 2043420..2044076 (-) 657 WP_369187178.1 MBL fold metallo-hydrolase -
  AB5J58_RS09520 (AB5J58_09520) - 2044087..2044773 (-) 687 WP_369187179.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  AB5J58_RS09525 (AB5J58_09525) uvrA 2044999..2047995 (+) 2997 WP_369187180.1 excinuclease ABC subunit UvrA Machinery gene
  AB5J58_RS09530 (AB5J58_09530) - 2048123..2049034 (-) 912 WP_369187181.1 carbohydrate kinase -
  AB5J58_RS09535 (AB5J58_09535) - 2049082..2050140 (-) 1059 WP_369187182.1 LacI family DNA-binding transcriptional regulator -
  AB5J58_RS09540 (AB5J58_09540) - 2050362..2050784 (+) 423 WP_329555550.1 Rieske (2Fe-2S) protein -
  AB5J58_RS09545 (AB5J58_09545) - 2050811..2051758 (-) 948 WP_329555551.1 hypothetical protein -
  AB5J58_RS09550 (AB5J58_09550) - 2051972..2052343 (-) 372 WP_369187183.1 response regulator -

Sequence

Protein


Download         Length: 998 a.a.        Molecular weight: 109402.47 Da        Isoelectric Point: 7.1455

>NTDB_id=924910 AB5J58_RS09525 WP_369187180.1 2044999..2047995(+) (uvrA) [Streptomyces sp. R08]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPISRQSPQAVVDKVLALPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGEIIQLSEPPTLKKQEKHTIEVVIDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPECSGIGTRMEVDAELIVPDEDKSLDEGAIHPWSHGHTK
DYFGRLIGALADALGFRTDIPFAGLPQRAKKALLYGHKTQIEVRYRNRYGRERVYTTPFEGAVPFVKRRHGEAESDASRE
RFEGYMREVPCPTCHGTRLKPVVLAVTIMDKSIAEISGMSISDCAEFLGGMKLDARDKKIAERVLKECNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WIVDIGPGAGEHGGKVVHSGSLKELLANDESMTGQYLSGKKAIPLPDIRRPRDLSRQLTVHGARENNLQDIDVSFPLGVF
TAVTGVSGSGKSTLVNDILYTHLARELNGARNVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLFA
ETTEAKVRGYLPGRFSFNVKGGRCENCAGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLDVHYKGKSIADVLNMPIEEA
TEFFEAVPGIARHLNTLKDVGLGYVRLGQSATTLSGGEAQRVKLASELQRRSTGRTVYVLDEPTTGLHFEDISKLLTVLG
GLVDKGNTVIVIEHNLDVIKVADWVVDMGPEGGAGGGLVIAEGTPEEVAAVSTSHTGKFLREILDADQISDGAPVKAPRK
TAAKKTAAVAAKKAAPAKKAAPAKKSAPAKKTTRARKA

Nucleotide


Download         Length: 2997 bp        

>NTDB_id=924910 AB5J58_RS09525 WP_369187180.1 2044999..2047995(+) (uvrA) [Streptomyces sp. R08]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAATCTGAAGAATGTCTCGCTCGACCTGCCACGCGACTCGCT
CATCGTTTTCACGGGCCTGTCCGGGTCGGGCAAGTCCTCCCTGGCCTTCGACACGATCTTCGCCGAGGGCCAGCGGCGCT
ACGTGGAATCGCTCTCCTCGTACGCCCGCCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAAGGTCTG
TCCCCGGCCGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTGCGCCTGCTCTTCGCGCGCATCGGCAAGCCGCACTGCCCCGAGTGCGGCCGGCCCATCTCGCGCCAGTCGCCGC
AGGCCGTCGTCGACAAGGTCCTGGCGCTGCCCGAGGGCAGCCGCTTCCAGGTCCTGTCGCCGCTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTGTTCGCCGACCTCCAGACCAAGGGCTACAGCCGCGCGCGCGTGGACGGCGAGATCATCCAGCT
CTCCGAGCCGCCCACCCTGAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCATCGACCGCCTCACGGTGAAGGACTCCG
CCAAGCGCCGTCTCACGGACTCCGTGGAGACCGCCCTCGGGCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGCATGTACTCGGAGCACCTGTACTGCCCGTACGACGACCTGTCCTTCGAGGAGCT
GGAGCCCCGCTCCTTCTCCTTCAACTCGCCGTTCGGCGCCTGCCCCGAGTGCTCCGGCATCGGCACGCGCATGGAGGTCG
ACGCCGAGCTGATCGTCCCGGACGAGGACAAGTCCCTGGACGAGGGTGCCATCCACCCCTGGTCGCACGGCCACACCAAG
GACTACTTCGGCCGTCTCATCGGCGCCCTCGCGGACGCGCTGGGCTTCCGCACCGACATCCCCTTCGCGGGCCTCCCGCA
GCGCGCCAAGAAGGCCCTGCTCTACGGCCACAAGACGCAGATCGAGGTCCGGTACCGCAACAGGTACGGCCGCGAGCGGG
TCTACACGACGCCCTTCGAAGGCGCCGTCCCCTTCGTGAAGCGCCGGCACGGCGAGGCGGAGAGCGACGCCAGCCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACGTGTCACGGCACGCGCCTGAAGCCCGTCGTCCTCGCGGTCAC
GATCATGGACAAGTCGATCGCCGAGATCTCCGGGATGTCGATCAGCGACTGCGCGGAGTTCCTGGGCGGGATGAAGCTCG
ACGCCCGCGACAAGAAGATCGCCGAGCGCGTCCTGAAGGAGTGCAACGAGAGGCTGCGCTTCCTGGTCGACGTAGGCCTC
GACTACCTCTCGTTGAACCGCGCGGCCGGCACCCTCTCCGGCGGCGAGGCCCAGCGCATCCGCCTGGCCACGCAGATCGG
CTCCGGCCTCGTGGGCGTCCTGTACGTCCTGGACGAGCCGTCCATCGGCCTGCACCAGCGCGACAACCACCGGCTGATCG
AGACCCTGGTCCGGCTCCGTGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACCATCAAGGTCGCCGAC
TGGATCGTCGACATCGGCCCCGGCGCGGGCGAGCACGGCGGCAAGGTCGTGCACAGCGGCTCCCTGAAGGAGCTGCTCGC
CAACGACGAGTCGATGACCGGGCAGTACCTGTCCGGCAAGAAGGCCATCCCGCTGCCCGACATCCGGCGCCCGCGCGACC
TCTCGCGCCAGCTCACGGTGCACGGCGCCCGGGAGAACAACCTCCAGGACATCGACGTCTCGTTCCCCCTGGGCGTGTTC
ACCGCGGTCACCGGCGTCTCCGGCTCCGGCAAGTCGACCCTGGTCAACGACATCCTGTACACCCACCTCGCCCGCGAGCT
GAACGGCGCGAGGAACGTGCCGGGACGCCACACGCGCGTGGACGGCGACGACCTCGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCCATCGGCCGCACCCCGCGGTCGAATCCGGCGACGTACACCGGAGTCTTCGACCACGTCCGCAAGCTGTTCGCC
GAGACGACCGAGGCGAAGGTGCGCGGGTATCTGCCCGGCCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAACTG
CGCGGGCGACGGCACCATCAAGATCGAGATGAACTTCCTGCCGGACGTCTACGTCCCGTGCGAGGTGTGCCACGGCGCCC
GGTACAACCGGGAGACGCTGGACGTCCACTACAAGGGCAAGTCCATCGCCGACGTCCTGAACATGCCGATCGAGGAGGCC
ACGGAGTTCTTCGAGGCGGTCCCCGGGATCGCCCGCCACCTCAACACCCTCAAGGACGTCGGCCTGGGCTACGTCCGGCT
CGGCCAGTCCGCGACCACCCTGTCCGGCGGTGAGGCCCAGCGCGTCAAGCTCGCCAGCGAGCTCCAGCGCCGCTCCACCG
GCCGTACGGTCTACGTCCTGGACGAGCCGACCACCGGCCTGCACTTCGAGGACATCAGCAAGCTCCTCACGGTGCTCGGC
GGCCTGGTCGACAAGGGCAACACGGTCATCGTCATCGAGCACAACCTCGACGTGATCAAGGTCGCCGACTGGGTCGTCGA
CATGGGTCCGGAGGGTGGCGCGGGCGGCGGCCTGGTCATCGCCGAGGGCACACCGGAGGAGGTGGCCGCGGTCTCGACCA
GCCACACCGGCAAGTTCCTCCGCGAGATCCTCGACGCCGACCAGATCAGCGACGGCGCCCCGGTGAAGGCCCCGCGCAAG
ACGGCGGCCAAGAAGACCGCGGCGGTCGCGGCGAAGAAGGCGGCGCCCGCCAAGAAGGCCGCTCCGGCGAAGAAGTCGGC
GCCCGCGAAGAAGACGACTCGGGCCCGCAAGGCCTGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(628-864)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)

UvrA interaction domain (UvrA_inter)

(131-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.825

94.689

0.538
  uvrA Streptococcus pneumoniae TIGR4

56.825

94.689

0.538
  uvrA Streptococcus pneumoniae D39

56.825

94.689

0.538