Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AB3470_RS18060 Genome accession   NZ_CP162517
Coordinates   3387275..3388651 (-) Length   458 a.a.
NCBI ID   WP_029725912.1    Uniprot ID   -
Organism   Bacillus subtilis strain BF12B1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3382275..3393651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3470_RS18035 (AB3470_18025) feuV 3382316..3383143 (-) 828 WP_010886609.1 ABC transporter ATP-binding protein -
  AB3470_RS18040 (AB3470_18030) cotNW 3383361..3383798 (-) 438 WP_029725909.1 YusW family protein -
  AB3470_RS18045 (AB3470_18035) - 3383908..3385704 (-) 1797 WP_029725910.1 M3 family oligoendopeptidase -
  AB3470_RS18050 (AB3470_18040) yusZ 3385839..3386681 (+) 843 WP_029725911.1 oxidoreductase -
  AB3470_RS18055 (AB3470_18045) mrgA 3386771..3387232 (+) 462 WP_015714679.1 metalloregulation DNA-binding stress protein MgrA -
  AB3470_RS18060 (AB3470_18050) htrA 3387275..3388651 (-) 1377 WP_029725912.1 serine protease Do-like protein HtrB Regulator
  AB3470_RS18065 (AB3470_18055) cssR 3388929..3389606 (+) 678 WP_003228529.1 secretion stress-responsive two-component system response regulator CssR -
  AB3470_RS18070 (AB3470_18060) cssS 3389603..3390958 (+) 1356 WP_003228527.1 secretion stress-responsive two-component system sensor histidine kinase CssS -
  AB3470_RS18075 (AB3470_18065) spxO 3390986..3391150 (-) 165 WP_003221681.1 anti-adapter protein SpxO -
  AB3470_RS18080 (AB3470_18070) spxN 3391318..3392193 (+) 876 WP_003243192.1 TetR/AcrR family transcriptional regulator -
  AB3470_RS18085 (AB3470_18075) fumC 3392233..3393621 (-) 1389 WP_003228523.1 class II fumarate hydratase -

Sequence

Protein


Download         Length: 458 a.a.        Molecular weight: 48747.21 Da        Isoelectric Point: 4.5582

>NTDB_id=923908 AB3470_RS18060 WP_029725912.1 3387275..3388651(-) (htrA) [Bacillus subtilis strain BF12B1]
MDYRRDGQNDQHQTEPSHTEQQNTENQKLIGHSEQELLDAPVSYEAGRQETASALEMEKQETAVKKEKKRRAAWLSPILG
GIIGGGLMLGIAPYLPSDQNQTTETASANKQVQSDNFTTAPITNASNIADMVEDLEPTIVGISNIQTSQNNTFGTGGGSS
SESESGTGSGVIFKKDSDKAYIITNNHVVEGANKLTVTLYNGETETAKLVGSDTITDLAVLEISGKNVKKVASFGDSSQL
RTGEKVIAIGNPLGQQFSGTVTQGIISGLNRTIDVDTTQGTVEMNVLQTDAAINPGNSGGPLINASGQVIGINSLKVSES
GVESLGFAIPSNDVEPIVDQLLQNGKVDRPFLGVQMIDMSQVPETYQENTLGLFGDQLGKGVYVKEVQANSPAEKAGIKS
EDVIVKLNGKDVESSADIRQILYKDLKVGDKTTIQVLRKGKTKTLNATLTKQTESSSS

Nucleotide


Download         Length: 1377 bp        

>NTDB_id=923908 AB3470_RS18060 WP_029725912.1 3387275..3388651(-) (htrA) [Bacillus subtilis strain BF12B1]
TTGGATTATCGACGTGATGGCCAAAACGATCAACATCAAACTGAACCTTCACATACAGAACAGCAGAATACAGAAAACCA
GAAGCTGATTGGACATTCTGAACAAGAATTGCTTGACGCGCCTGTGTCGTATGAAGCGGGACGGCAGGAAACGGCTTCTG
CTTTAGAAATGGAAAAGCAAGAAACGGCTGTGAAAAAAGAAAAGAAACGGAGAGCCGCATGGCTGAGCCCGATTTTAGGC
GGTATTATCGGCGGGGGCCTCATGCTTGGCATCGCGCCTTATCTGCCGTCAGACCAAAATCAGACGACCGAGACCGCTTC
CGCAAATAAACAGGTGCAGTCTGATAATTTTACAACGGCGCCGATAACGAACGCATCAAACATCGCTGATATGGTAGAGG
ATTTAGAGCCTACGATTGTCGGAATCTCAAATATCCAAACCTCTCAAAATAACACATTCGGCACGGGAGGAGGCTCCAGC
TCAGAAAGTGAAAGCGGAACCGGTTCAGGTGTCATTTTCAAAAAAGACAGCGATAAAGCGTATATCATTACAAACAACCA
TGTCGTTGAAGGCGCGAACAAGCTGACTGTTACGCTATACAACGGAGAAACGGAAACTGCCAAGCTTGTCGGCAGCGATA
CCATTACTGATTTGGCAGTTTTGGAAATCAGCGGCAAGAACGTCAAAAAAGTGGCGAGCTTTGGTGATTCTTCGCAGCTG
CGCACTGGCGAAAAGGTAATCGCTATCGGTAACCCGCTCGGACAGCAGTTTTCCGGTACGGTGACACAAGGCATCATTAG
CGGACTGAACCGGACAATTGATGTGGATACAACACAAGGGACGGTGGAAATGAACGTGCTGCAAACCGATGCAGCGATCA
ATCCGGGGAACAGCGGAGGCCCATTAATCAATGCAAGCGGCCAGGTCATCGGCATCAACAGCTTGAAGGTGAGCGAAAGC
GGCGTGGAATCACTTGGATTTGCGATCCCAAGCAATGATGTCGAGCCAATTGTTGACCAGCTGCTGCAAAACGGGAAGGT
GGACCGTCCGTTTTTAGGCGTGCAGATGATTGACATGTCACAAGTTCCTGAAACCTATCAGGAAAATACGCTCGGCCTGT
TTGGAGATCAATTGGGCAAAGGTGTTTATGTAAAAGAAGTTCAAGCAAATTCGCCGGCAGAAAAAGCAGGTATTAAATCT
GAGGATGTCATTGTCAAACTAAACGGTAAAGACGTGGAAAGCAGTGCGGATATCCGTCAGATCCTTTACAAAGACTTAAA
AGTCGGAGATAAAACAACAATCCAAGTGCTGCGAAAGGGAAAAACGAAAACGTTGAACGCGACACTGACCAAGCAGACAG
AAAGCAGTTCAAGCTAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(350-449)

Trypsin-like peptidase domain (Trypsin_2)

(168-312)

Peptidase family M50 (Peptidase_M50)

(282-455)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

41.353

87.118

0.36