Detailed information NTG0923771

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: AB3452_RS12635
• Genome accession: NZ_CP162478
• Coordinates: 2545562..2546644 (-)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain TUM20816
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2540562..2551644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3452_RS12615 (AB3452_12615)	-	2541171..2541275 (-)	105	WP_001790092.1	hypothetical protein	-
AB3452_RS12620 (AB3452_12620)	secA	2541317..2543848 (-)	2532	WP_000506531.1	preprotein translocase subunit SecA	-
AB3452_RS12625 (AB3452_12625)	raiA	2544262..2544834 (-)	573	WP_000617735.1	ribosome-associated translation inhibitor RaiA	-
AB3452_RS12630 (AB3452_12630)	-	2544895..2545569 (-)	675	WP_001057965.1	ComF family protein	-
AB3452_RS12635 (AB3452_12635)	comFA	2545562..2546644 (-)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
AB3452_RS12640 (AB3452_12640)	fakB1	2547008..2547874 (-)	867	WP_000686342.1	fatty acid kinase binding subunit FakB1	-
AB3452_RS12645 (AB3452_12645)	-	2548018..2548659 (+)	642	WP_000192947.1	YigZ family protein	-
AB3452_RS12650 (AB3452_12650)	-	2548829..2549884 (-)	1056	WP_000258151.1	glycosyltransferase family 4 protein	-
AB3452_RS12655 (AB3452_12655)	-	2550202..2551272 (+)	1071	WP_000460983.1	GGDEF domain-containing protein	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=923771 AB3452_RS12635 WP_001548033.1 2545562..2546644(-) (comFA) [Staphylococcus aureus strain TUM20816]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=923771 AB3452_RS12635 WP_001548033.1 2545562..2546644(-) (comFA) [Staphylococcus aureus strain TUM20816]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATTTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGGGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367