Detailed information NTG0923297

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: AB3431_RS09890
• Genome accession: NZ_CP162467
• Coordinates: 1957462..1960308 (+)
• Length: 948 a.a.
• NCBI ID: WP_000662681.1
• Uniprot ID: Q8NXL9
• Organism: Staphylococcus aureus strain TUM20823
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1952462..1965308

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3431_RS09865 (AB3431_09865)	-	1953049..1953156 (+)	108	WP_001790093.1	hypothetical protein	-
AB3431_RS09870 (AB3431_09870)	-	1953304..1954143 (+)	840	Protein_1897	CHAP domain-containing protein	-
AB3431_RS09875 (AB3431_09875)	-	1954317..1954967 (+)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
AB3431_RS09880 (AB3431_09880)	-	1954964..1955200 (+)	237	WP_000638419.1	CsbA family protein	-
AB3431_RS09885 (AB3431_09885)	uvrB	1955469..1957454 (+)	1986	WP_000229253.1	excinuclease ABC subunit UvrB	Machinery gene
AB3431_RS09890 (AB3431_09890)	uvrA	1957462..1960308 (+)	2847	WP_000662681.1	excinuclease ABC subunit UvrA	Machinery gene
AB3431_RS09895 (AB3431_09895)	hprK	1960970..1961902 (+)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-
AB3431_RS09900 (AB3431_09900)	lgt	1961908..1962747 (+)	840	WP_000513308.1	prolipoprotein diacylglyceryl transferase	-
AB3431_RS09905 (AB3431_09905)	-	1962755..1963240 (+)	486	WP_001224793.1	DapH/DapD/GlmU-related protein	-
AB3431_RS09910 (AB3431_09910)	-	1963248..1964687 (+)	1440	WP_000057542.1	lipopolysaccharide assembly protein LapB	-

Sequence

Protein

• Length: 948 a.a.
• Molecular weight: 105368.12 Da
• Isoelectric Point: 6.2757

>NTDB_id=923297 AB3431_RS09890 WP_000662681.1 1957462..1960308(+) (uvrA) [Staphylococcus aureus strain TUM20823]
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEG
LSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR
KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID
GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTL
LKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKY
MTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL
NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDI
GPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGV
SGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK
IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFEN
IPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENG
DTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK

Nucleotide

• Length: 2847 bp

>NTDB_id=923297 AB3431_RS09890 WP_000662681.1 1957462..1960308(+) (uvrA) [Staphylococcus aureus strain TUM20823]
ATGAAAGAACCATCCATAGTAGTAAAAGGTGCTCGTGCGCATAACTTGAAAGATATTGATATCGAACTACCTAAAAATAA
ATTAATTGTTATGACAGGTTTATCTGGGTCAGGTAAATCGTCATTAGCATTCGATACTATATATGCTGAAGGACAACGAC
GTTATGTTGAATCATTAAGTGCCTATGCGCGTCAATTTTTAGGCCAAATGGACAAACCAGATGTTGATACAATTGAAGGA
TTATCGCCAGCAATTTCAATAGATCAAAAAACAACAAGTAAAAATCCAAGATCAACTGTAGCAACAGTAACAGAAATATA
TGATTATATACGTTTGTTATATGCACGTGTTGGTAAACCTTACTGTCCAAATCACAATATAGAAATTGAATCGCAAACAG
TACAACAAATGGTTGACCGCATTATGGAATTAGAGGCACGTACAAAGATTCAATTATTAGCACCTGTCATCGCTCATCGT
AAAGGTAGTCATGAAAAGCTAATCGAAGATATTGGTAAAAAAGGTTATGTACGTTTAAGAATCGATGGCGAAATTGTTGA
TGTAAATGATGTACCTACTTTAGATAAGAACAAGAATCATACAATAGAAGTTGTTGTAGACCGATTAGTTGTTAAAGATG
GAATTGAAACACGACTAGCTGACTCTATAGAAACTGCCTTAGAGCTTTCAGAAGGACAATTAACAGTCGATGTCATTGAC
GGGGAAGACCTTAAGTTTTCAGAAAGCCATGCTTGTCCTATATGTGGATTTTCAATCGGAGAGTTAGAACCAAGAATGTT
TAGCTTTAACAGTCCTTTTGGTGCTTGTCCGACATGTGATGGCTTAGGCCAAAAGTTAACAGTCGATGTAGACTTGGTTG
TTCCCGACAAAGATAAGACGCTAAACGAAGGTGCAATAGAACCTTGGATACCGACGAGTTCTGATTTTTATCCAACATTG
TTAAAACGTGTTTGTGAAGTTTATAAAATCAATATGGATAAACCTTTTAAAAAGTTAACAGAACGTCAACGTGATATTTT
ATTGTATGGTTCTGGTGACAAAGAAATTGAATTTACATTTACACAACGTCAAGGTGGTACTAGAAAACGAACAATGGTTT
TCGAGGGTGTAGTTCCTAATATAAGTAGACGATTCCATGAATCTCCTTCAGAATATACACGTGAAATGATGAGTAAATAT
ATGACTGAACTACCTTGCGAAACTTGTCATGGAAAGCGATTGAGTCGTGAAGCGTTATCTGTTTATGTAGGTGGTTTAAA
TATTGGTGAAGTAGTCGAATATTCAATCAGTCAAGCGCTGAACTATTATAAAAACATTGATTTGTCAGAACAAGATCAAG
CGATTGCAAATCAAATATTGAAAGAAATTATTTCCCGACTCACTTTTTTAAATAATGTGGGACTTGAATATTTAACGTTA
AACAGAGCTTCAGGTACACTTTCAGGTGGTGAAGCACAACGTATTCGATTAGCAACGCAAATTGGGTCGCGTTTGACTGG
TGTCTTATATGTATTAGATGAGCCATCAATTGGACTGCATCAAAGAGATAATGATCGATTAATTAATACACTTAAAGAAA
TGAGAGATTTAGGAAATACTTTAATTGTAGTTGAACACGATGATGATACAATGCGTGCGGCTGATTACTTAGTGGATATA
GGTCCTGGTGCTGGTGAACATGGAGGGCAGATTGTGTCTAGTGGTACTCCTCAAAAGGTAATGAAAGATAAAAAATCATT
AACAGGACAATACTTGAGTGGTAAGAAACGTATTGAAGTACCTGAATATCGCAGACCGGCTTCAGATCGTAAAATTTCTA
TACGTGGAGCTAGAAGCAACAATCTTAAAGGGGTTGATGTGGACATACCACTATCAATCATGACGGTTGTTACAGGTGTA
TCAGGTTCTGGTAAAAGCTCATTAGTAAATGAAGTATTATACAAATCATTAGCTCAAAAAATTAATAAATCTAAAGTAAA
GCCAGGATTGTACGATAAGATTGAAGGTATTGATCAACTTGATAAAATTATTGATATTGATCAATCACCAATAGGTAGAA
CGCCACGCTCTAATCCAGCAACATATACTGGTGTGTTTGATGATATACGTGATGTGTTTGCGCAAACAAATGAAGCTAAA
ATTCGAGGATATCAAAAAGGGCGTTTTAGTTTTAATGTAAAAGGTGGACGCTGTGAAGCTTGTAAAGGTGACGGTATTAT
TAAAATTGAAATGCATTTTTTACCTGATGTTTATGTTCCTTGTGAAGTGTGTGATGGTAAACGATATAATCGTGAGACAC
TAGAGGTTACTTACAAAGGTAAAAATATTGCTGACATTTTAGAAATGACTGTTGAAGAAGCAACACAATTTTTTGAAAAT
ATTCCTAAGATTAAGCGCAAGTTACAAACACTAGTTGATGTTGGTCTTGGATACGTCACATTAGGTCAACAAGCTACAAC
GTTATCAGGTGGTGAGGCTCAACGTGTGAAACTTGCATCTGAACTTCATAAACGTTCAACTGGTAAATCTATTTATATCC
TAGATGAACCGACAACAGGGTTACATGTTGACGATATTAGTAGATTATTAAAAGTATTAAACCGATTAGTTGAAAATGGT
GATACTGTTGTAATTATTGAACATAACCTAGATGTTATCAAAACAGCAGACTATATTATAGACTTAGGTCCTGAAGGTGG
TAGTGGCGGTGGTACTATTGTTGCGACTGGCACACCCGAAGATATTGCTCAGACAAAGTCATCATATACAGGAAAGTATT
TAAAAGAAGTACTTGAACGAGATAAACAAAATACTGAAGATAAATAA

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-399)

• ABC transporter (ABC_tran) (622-858)

3D structure

• AlphaFold DB: Q8NXL9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	66.773	99.051	0.661
uvrA	Streptococcus pneumoniae TIGR4	66.773	99.051	0.661
uvrA	Streptococcus pneumoniae D39	66.773	99.051	0.661