Detailed information NTG0923277

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: AB3431_RS05085
• Genome accession: NZ_CP162467
• Coordinates: 960911..963007 (+)
• Length: 698 a.a.
• NCBI ID: WP_368410400.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain TUM20823
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 955911..968007

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3431_RS05060 (AB3431_05060)	-	956050..956184 (-)	135	WP_001789912.1	hypothetical protein	-
AB3431_RS05065 (AB3431_05065)	-	956278..956535 (-)	258	WP_000402605.1	hypothetical protein	-
AB3431_RS05070 (AB3431_05070)	-	957114..958391 (-)	1278	WP_001180323.1	hydroxymethylglutaryl-CoA reductase, degradative	-
AB3431_RS05075 (AB3431_05075)	-	958645..959811 (+)	1167	WP_000151982.1	hydroxymethylglutaryl-CoA synthase	-
AB3431_RS05080 (AB3431_05080)	-	959981..960502 (-)	522	WP_000455987.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
AB3431_RS05085 (AB3431_05085)	clpE	960911..963007 (+)	2097	WP_368410400.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
AB3431_RS05090 (AB3431_05090)	-	963076..963246 (-)	171	WP_000111118.1	FeoB-associated Cys-rich membrane protein	-
AB3431_RS05095 (AB3431_05095)	feoB	963259..965253 (-)	1995	WP_000432907.1	ferrous iron transport protein B	-
AB3431_RS05100 (AB3431_05100)	-	965265..965492 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 77580.94 Da
• Isoelectric Point: 4.5863

>NTDB_id=923277 AB3431_RS05085 WP_368410400.1 960911..963007(+) (clpE) [Staphylococcus aureus strain TUM20823]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGGNGNYLEQ
IGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDIS
SLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSDSKGLSDILKPALSRGEISIIGATTQDEYRN
NILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHL
SAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQM
DDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDALIR
LDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFK
NTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQD
AKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2097 bp

>NTDB_id=923277 AB3431_RS05085 WP_368410400.1 960911..963007(+) (clpE) [Staphylococcus aureus strain TUM20823]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGAAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGTGGCAACGGCAATTATTTAGAACAA
ATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAATTCAAGAAAC
TGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTGCGATTGTTG
AAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTAGACATTTCA
TCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAAATCTTCACA
AAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGATAGCAAAGGGT
TATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAATATCGAAAC
AATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTGCTTGTTAATGAACCAAGCGCTAAAGATACTGTTGA
AATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAGCATGTGTTG
ACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCAGCACATTTA
TCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACGTAAAGCAGT
AAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAAATAGTAATG
GTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTTTCTCAAATG
GATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCAAGCTGTAGA
AATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCCTATTTGTTG
GCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATTTATTTGGTAATAAAGATGCACTGATTCGA
CTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTTGGTTATGATGA
CAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAAAAGCAAATC
CACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATCAACTTTAAA
AATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACGCTGAAGAAAAAGATATTATGCACGAAAT
GAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAGATGCATTGC
AAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGACAAAAAAGGTATTACGATGGACGTTTCTCAAGAT
GCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGAACAGCAAGT
ACGTGACAAAATTACAGATTACTATTTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATAACGAATTAG
TCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (261-360)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-679)

• AAA domain (Cdc48 subfamily) (AAA_2) (445-600)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-254)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.682	92.407	0.45
clpC	Lactococcus lactis subsp. cremoris KW2	45.745	94.269	0.431
clpE	Streptococcus pneumoniae Rx1	48.298	88.395	0.427
clpE	Streptococcus pneumoniae D39	48.298	88.395	0.427
clpE	Streptococcus pneumoniae R6	48.298	88.395	0.427
clpE	Streptococcus pneumoniae TIGR4	48.298	88.395	0.427
clpC	Bacillus subtilis subsp. subtilis str. 168	44.394	94.556	0.42
clpC	Streptococcus pneumoniae Rx1	43.053	93.84	0.404
clpC	Streptococcus pneumoniae TIGR4	43.053	93.84	0.404
clpC	Streptococcus pneumoniae D39	43.053	93.84	0.404
clpC	Streptococcus thermophilus LMD-9	44.603	90.258	0.403
clpC	Streptococcus thermophilus LMG 18311	44.286	90.258	0.4
clpC	Streptococcus mutans UA159	43.577	88.109	0.384
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.536	89.255	0.38