Detailed information NTG0922294

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: AB3441_RS03375
• Genome accession: NZ_CP162444
• Coordinates: 704817..706913 (-)
• Length: 698 a.a.
• NCBI ID: WP_108932443.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain TUM22182
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 699817..711913

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3441_RS03360 (AB3441_03360)	-	702332..702559 (+)	228	WP_000932073.1	FeoA family protein	-
AB3441_RS03365 (AB3441_03365)	feoB	702571..704565 (+)	1995	WP_000432907.1	ferrous iron transport protein B	-
AB3441_RS03370 (AB3441_03370)	-	704578..704748 (+)	171	WP_000111118.1	FeoB-associated Cys-rich membrane protein	-
AB3441_RS03375 (AB3441_03375)	clpE	704817..706913 (-)	2097	WP_108932443.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
AB3441_RS03380 (AB3441_03380)	-	707322..707843 (+)	522	WP_000455987.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
AB3441_RS03385 (AB3441_03385)	-	708013..709179 (-)	1167	WP_000151982.1	hydroxymethylglutaryl-CoA synthase	-
AB3441_RS03390 (AB3441_03390)	-	709433..710710 (+)	1278	WP_001180323.1	hydroxymethylglutaryl-CoA reductase, degradative	-
AB3441_RS03395 (AB3441_03395)	-	711289..711546 (+)	258	WP_000402605.1	hypothetical protein	-
AB3441_RS03400 (AB3441_03400)	-	711640..711774 (+)	135	WP_001789912.1	hypothetical protein	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 77522.90 Da
• Isoelectric Point: 4.6056

>NTDB_id=922294 AB3441_RS03375 WP_108932443.1 704817..706913(-) (clpE) [Staphylococcus aureus strain TUM22182]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGGNGNYLEQ
IGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDIS
SLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDEYRN
NILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHL
SAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQM
DDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDALIR
LDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFK
NTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQD
AKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2097 bp

>NTDB_id=922294 AB3441_RS03375 WP_108932443.1 704817..706913(-) (clpE) [Staphylococcus aureus strain TUM22182]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGAAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGTGGCAACGGCAATTATTTAGAACAA
ATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAATTCAAGAAAC
TGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTGCGATTGTTG
AAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTAGACATTTCA
TCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAAATCTTCACA
AAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTAGCAAAGGGT
TATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAATATCGAAAC
AATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTGCTTGTTAATGAACCAAGCGCTAAAGATACTGTTGA
AATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAGCATGTGTTG
ACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCAGCACATTTA
TCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACGTAAAGCAGT
AAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAAATAGTAATG
GTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTTTCTCAAATG
GATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCAAGCTGTAGA
AATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCCTATTTGTTG
GCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATTTATTTGGTAATAAAGATGCACTGATTCGA
CTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTTGGTTATGATGA
CAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAAAAGCAAATC
CACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATCAACTTTAAA
AATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACGCTGAAGAAAAAGATATTATGCACGAAAT
GAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAGATGCATTGC
AAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGACAAAAAAGGTATTACGATGGACGTTTCTCAAGAT
GCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGAACAGCAAGT
ACGTGACAAAATTACAGATTACTATTTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATAACGAATTAG
TCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (261-360)

• AAA domain (Cdc48 subfamily) (AAA_2) (445-600)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-254)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.682	92.407	0.45
clpC	Lactococcus lactis subsp. cremoris KW2	45.745	94.269	0.431
clpE	Streptococcus pneumoniae Rx1	48.298	88.395	0.427
clpE	Streptococcus pneumoniae D39	48.298	88.395	0.427
clpE	Streptococcus pneumoniae R6	48.298	88.395	0.427
clpE	Streptococcus pneumoniae TIGR4	48.298	88.395	0.427
clpC	Bacillus subtilis subsp. subtilis str. 168	44.394	94.556	0.42
clpC	Streptococcus pneumoniae Rx1	43.053	93.84	0.404
clpC	Streptococcus pneumoniae TIGR4	43.053	93.84	0.404
clpC	Streptococcus pneumoniae D39	43.053	93.84	0.404
clpC	Streptococcus thermophilus LMD-9	44.603	90.258	0.403
clpC	Streptococcus thermophilus LMG 18311	44.286	90.258	0.4
clpC	Streptococcus mutans UA159	43.577	88.109	0.384
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.536	89.255	0.38