Detailed information NTG0921954

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: VP456_RS18685
• Genome accession: NZ_CP142142
• Coordinates: 3704637..3705800 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain PD9
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3699637..3710800

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VP456_RS18655 (VP456_18590)	-	3699902..3700321 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
VP456_RS18660 (VP456_18595)	comFC	3700395..3701084 (-)	690	WP_202627211.1	ComF family protein	Machinery gene
VP456_RS18665 (VP456_18600)	-	3701090..3701374 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
VP456_RS18670 (VP456_18605)	comFA	3701432..3702817 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
VP456_RS18675 (VP456_18610)	-	3702925..3703773 (-)	849	WP_003151387.1	DegV family protein	-
VP456_RS18680 (VP456_18615)	degU	3703871..3704560 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
VP456_RS18685 (VP456_18620)	degS	3704637..3705800 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
VP456_RS18690 (VP456_18625)	-	3706023..3706670 (+)	648	WP_007614107.1	YigZ family protein	-
VP456_RS18695 (VP456_18630)	-	3706675..3707889 (+)	1215	WP_014419013.1	LCP family protein	-
VP456_RS18700 (VP456_18635)	-	3707988..3709064 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
VP456_RS18705 (VP456_18640)	-	3709197..3710393 (-)	1197	WP_029972825.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=921954 VP456_RS18685 WP_007407484.1 3704637..3705800(-) (degS) [Bacillus velezensis strain PD9]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=921954 VP456_RS18685 WP_007407484.1 3704637..3705800(-) (degS) [Bacillus velezensis strain PD9]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTTATCATTAAGGACAACGGAAAAGGTTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951