Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VP456_RS06525 Genome accession   NZ_CP142142
Coordinates   1227526..1228182 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain PD9     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1222526..1233182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VP456_RS06500 (VP456_06470) oppF 1223055..1223972 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  VP456_RS06505 (VP456_06475) - 1224079..1225266 (+) 1188 WP_029973145.1 putative glycoside hydrolase -
  VP456_RS06510 (VP456_06480) - 1225384..1225962 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  VP456_RS06515 (VP456_06485) spx 1226141..1226536 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  VP456_RS06520 (VP456_06490) - 1226594..1227250 (-) 657 WP_014417421.1 TerC family protein -
  VP456_RS06525 (VP456_06495) mecA 1227526..1228182 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  VP456_RS06530 (VP456_06500) - 1228333..1229493 (+) 1161 WP_029973144.1 competence protein CoiA family protein -
  VP456_RS06535 (VP456_06505) pepF 1229721..1231550 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  VP456_RS06540 (VP456_06510) - 1231588..1231755 (-) 168 WP_003155026.1 hypothetical protein -
  VP456_RS06545 (VP456_06515) spxH 1232042..1232944 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=921911 VP456_RS06525 WP_003155032.1 1227526..1228182(+) (mecA) [Bacillus velezensis strain PD9]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=921911 VP456_RS06525 WP_003155032.1 1227526..1228182(+) (mecA) [Bacillus velezensis strain PD9]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895