Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   VRA24_RS09975 Genome accession   NZ_CP142106
Coordinates   1971139..1972941 (+) Length   600 a.a.
NCBI ID   WP_013440239.1    Uniprot ID   -
Organism   Lactobacillus delbrueckii subsp. bulgaricus strain SCB0695     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1951479..1970817 1971139..1972941 flank 322


Gene organization within MGE regions


Location: 1951479..1972941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VRA24_RS09875 (VRA24_09875) - 1951479..1952237 (-) 759 WP_013440222.1 C40 family peptidase -
  VRA24_RS09880 (VRA24_09880) - 1952533..1953246 (-) 714 WP_013440223.1 C40 family peptidase -
  VRA24_RS09885 (VRA24_09885) - 1953400..1954182 (-) 783 WP_013440224.1 C40 family peptidase -
  VRA24_RS09890 (VRA24_09890) - 1954372..1954845 (-) 474 WP_013440225.1 C40 family peptidase -
  VRA24_RS09895 (VRA24_09895) - 1955015..1956061 (-) 1047 WP_013440226.1 2-hydroxyacid dehydrogenase -
  VRA24_RS09900 (VRA24_09900) - 1956345..1956830 (-) 486 WP_013440227.1 C40 family peptidase -
  VRA24_RS09905 (VRA24_09905) - 1956955..1957497 (-) 543 WP_003611236.1 guanylate kinase -
  VRA24_RS09910 (VRA24_09910) - 1957587..1957925 (+) 339 WP_013440228.1 DUF2187 family protein -
  VRA24_RS09915 (VRA24_09915) - 1957989..1959527 (+) 1539 WP_013440229.1 O-antigen ligase family protein -
  VRA24_RS09920 (VRA24_09920) - 1959580..1960206 (-) 627 WP_013440230.1 LVIS_2131 family protein -
  VRA24_RS09925 (VRA24_09925) - 1960209..1960724 (-) 516 WP_002879488.1 hypothetical protein -
  VRA24_RS09930 (VRA24_09930) - 1961278..1961946 (+) 669 WP_013440231.1 IS607 family transposase -
  VRA24_RS09935 (VRA24_09935) - 1961915..1963621 (+) 1707 WP_013440232.1 RNA-guided endonuclease TnpB family protein -
  VRA24_RS09940 (VRA24_09940) - 1964023..1964457 (+) 435 WP_180754090.1 hypothetical protein -
  VRA24_RS09945 (VRA24_09945) - 1964683..1965174 (-) 492 WP_013440234.1 threonine/serine exporter family protein -
  VRA24_RS09950 (VRA24_09950) - 1965177..1965932 (-) 756 WP_041812005.1 threonine/serine exporter family protein -
  VRA24_RS09955 (VRA24_09955) - 1965985..1967529 (-) 1545 WP_013440236.1 ABC-F family ATP-binding cassette domain-containing protein -
  VRA24_RS09960 (VRA24_09960) - 1967544..1967921 (-) 378 WP_002879494.1 hypothetical protein -
  VRA24_RS09965 (VRA24_09965) - 1968040..1969179 (-) 1140 WP_013440237.1 LCP family protein -
  VRA24_RS09970 (VRA24_09970) - 1969519..1970817 (+) 1299 WP_013440238.1 RNA-guided endonuclease InsQ/TnpB family protein -
  VRA24_RS09975 (VRA24_09975) pepF 1971139..1972941 (+) 1803 WP_013440239.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 68270.11 Da        Isoelectric Point: 4.4788

>NTDB_id=921719 VRA24_RS09975 WP_013440239.1 1971139..1972941(+) (pepF) [Lactobacillus delbrueckii subsp. bulgaricus strain SCB0695]
MEIPYRSEVPKEQTWDLTRIFKTEADWEAAFKAVKQEVKALPALEDGFTESAAVLYDRLTQIFAVDRRLSKIYVYASMAS
DVDTSNQKKLALNSRAQSLAAEYQAAVAFIQPAVLALGKEGLDAFFKEEPRLENYRHYLEQIVKQEEHVLPAEEEKLVSA
AGDALSASANTFNVLTNSDLQFPYIEGEDGEAVELTEANYDILIQSQNREVREDAFDALYAVYGQFASTFASTLAGNVKA
HNFDAQTHHYQDALAAALSENNIPVDVYNQLLTSVHKHLDLLHRYVNLREEILDLKGDLQMWDMYVPITGKPSLSYTFAE
AKAQAREALQVLGEDYVKHVDYLFNNRCIDHVANMHKQSGAYSGGAYDTDAYELLNWQGDLDSLYTLVHETGHSVHSMYT
RENQPYVYGDYPIFVAEIASTTNENLLTNYFLDRVTDPKTRAFLLNYYLSSFKGTVYRQTQFAEFEKFIHESDQAGEALT
ADYLCGFYDRLNQQYYGPAISLGSDIDLEWARIPHFYYNFYVYQYATGFAAATALANKITYGSQEDKEKYLDFLKSGSSD
YPINIMQKAGVDMTKSDYLEDAFKVFAERLDEFTDLIKKL

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=921719 VRA24_RS09975 WP_013440239.1 1971139..1972941(+) (pepF) [Lactobacillus delbrueckii subsp. bulgaricus strain SCB0695]
ATGGAAATCCCTTATCGCAGTGAGGTTCCCAAAGAACAGACCTGGGACTTGACCCGGATCTTCAAGACTGAGGCGGACTG
GGAGGCCGCCTTTAAAGCTGTCAAGCAGGAAGTCAAGGCCCTGCCGGCCTTGGAAGACGGCTTTACGGAGAGCGCGGCCG
TCCTCTATGACCGCTTGACCCAGATTTTTGCCGTTGACCGCCGCCTGTCCAAGATCTACGTCTATGCCAGCATGGCCAGC
GACGTCGACACCAGCAACCAGAAGAAGCTGGCCCTCAATTCCCGCGCCCAGAGCCTGGCCGCTGAATACCAGGCGGCTGT
TGCCTTCATTCAGCCGGCTGTTTTAGCCTTGGGGAAAGAGGGCCTGGACGCCTTTTTCAAGGAAGAGCCAAGACTGGAAA
ACTACCGGCACTATTTGGAACAGATCGTCAAGCAGGAAGAGCACGTTTTGCCAGCTGAAGAGGAGAAGCTGGTATCGGCG
GCCGGGGATGCCCTGTCAGCTTCGGCCAACACCTTCAACGTCTTGACCAACTCCGATTTGCAATTCCCTTACATTGAAGG
TGAAGACGGGGAAGCAGTGGAACTGACGGAAGCCAACTATGACATCTTGATCCAGTCCCAGAACCGGGAAGTCAGAGAGG
ACGCCTTTGACGCCCTTTACGCTGTCTACGGCCAGTTCGCGTCAACTTTTGCCTCAACCTTGGCCGGCAATGTCAAGGCC
CACAACTTTGATGCCCAGACCCACCACTACCAGGACGCCTTAGCCGCGGCTCTGTCAGAAAACAACATCCCTGTCGACGT
CTACAACCAGCTTTTGACTAGCGTCCACAAGCACCTGGACCTCCTCCACCGCTATGTCAACTTGCGCGAAGAGATCCTGG
ACCTGAAGGGCGACCTGCAAATGTGGGACATGTACGTGCCGATCACGGGCAAGCCAAGCCTCAGCTACACTTTCGCTGAA
GCCAAGGCCCAGGCCAGAGAGGCCCTGCAGGTTTTGGGCGAGGACTATGTCAAACACGTCGACTACCTCTTCAATAACCG
CTGCATCGACCACGTGGCTAACATGCACAAGCAAAGCGGGGCCTACTCCGGCGGGGCTTATGACACCGACGCCTATGAGC
TCTTGAACTGGCAGGGGGACCTGGATTCCCTCTACACCCTGGTCCACGAGACCGGCCACTCAGTCCACAGCATGTACACC
CGGGAAAACCAGCCATACGTGTACGGGGACTATCCGATCTTTGTCGCGGAAATTGCCTCAACGACCAATGAAAACCTGCT
GACCAACTACTTCCTGGATCGGGTGACGGATCCAAAGACCCGGGCCTTCCTGCTCAACTACTACTTGAGCTCCTTTAAGG
GAACGGTCTACCGGCAGACCCAGTTCGCGGAATTCGAGAAGTTCATTCATGAAAGCGACCAGGCGGGTGAAGCCTTGACG
GCTGACTACCTGTGTGGCTTCTACGACCGGCTCAACCAGCAGTACTACGGCCCGGCGATCAGCCTGGGCAGCGACATCGA
CCTGGAATGGGCCCGGATTCCTCACTTCTATTACAACTTCTACGTCTACCAGTACGCGACCGGCTTTGCCGCGGCGACTG
CCCTGGCTAACAAGATTACTTACGGCAGCCAGGAAGACAAGGAGAAGTACCTGGACTTCCTTAAGTCCGGCTCCAGCGAC
TACCCGATCAACATCATGCAGAAGGCCGGCGTCGACATGACCAAGTCCGACTACCTGGAAGATGCCTTCAAGGTCTTTGC
GGAAAGACTGGACGAATTTACTGACTTAATCAAAAAATTGTAG

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(203-584)

Oligopeptidase F (Peptidase_M3_N)

(115-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

50

99

0.495