Detailed information NTG0921659

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: VRA41_RS01435
• Genome accession: NZ_CP142105
• Coordinates: 264126..265025 (+)
• Length: 299 a.a.
• NCBI ID: WP_011226854.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain SCB0351
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 259126..270025

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VRA41_RS01415 (VRA41_01415)	trkA	260262..261611 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
VRA41_RS01420 (VRA41_01420)	-	261870..262409 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
VRA41_RS01425 (VRA41_01425)	-	262721..263278 (+)	558	WP_002949523.1	ECF transporter S component	-
VRA41_RS01430 (VRA41_01430)	-	263281..263931 (+)	651	WP_011226853.1	phosphatase PAP2 family protein	-
VRA41_RS01435 (VRA41_01435)	comR	264126..265025 (+)	900	WP_011226854.1	helix-turn-helix domain-containing protein	Regulator
VRA41_RS01440 (VRA41_01440)	-	265264..266442 (+)	1179	Protein_245	ABC transporter transmembrane domain-containing protein	-
VRA41_RS01445 (VRA41_01445)	-	266728..267296 (+)	569	Protein_246	ATP-binding cassette domain-containing protein	-
VRA41_RS01450 (VRA41_01450)	-	267404..267715 (+)	312	WP_011226857.1	DUF805 domain-containing protein	-
VRA41_RS01455 (VRA41_01455)	-	267683..267967 (-)	285	WP_231108755.1	hypothetical protein	-
VRA41_RS01460 (VRA41_01460)	-	268207..268509 (-)	303	WP_011226859.1	hypothetical protein	-
VRA41_RS01465 (VRA41_01465)	-	268733..269104 (-)	372	WP_231108754.1	hypothetical protein	-
VRA41_RS01470 (VRA41_01470)	-	269509..270024 (+)	516	WP_011226861.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35317.79 Da
• Isoelectric Point: 5.1073

>NTDB_id=921659 VRA41_RS01435 WP_011226854.1 264126..265025(+) (comR) [Streptococcus thermophilus strain SCB0351]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=921659 VRA41_RS01435 WP_011226854.1 264126..265025(+) (comR) [Streptococcus thermophilus strain SCB0351]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421