Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   VQ623_RS04390 Genome accession   NZ_CP142094
Coordinates   883345..884061 (-) Length   238 a.a.
NCBI ID   WP_037538035.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain MLK17     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 878345..889061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VQ623_RS04370 (VQ623_04370) - 878385..879629 (+) 1245 WP_317955901.1 ammonium transporter -
  VQ623_RS04375 (VQ623_04375) - 879730..880689 (+) 960 WP_107611700.1 LacI family DNA-binding transcriptional regulator -
  VQ623_RS04380 (VQ623_04380) - 880774..882258 (+) 1485 WP_107613506.1 sucrose-6-phosphate hydrolase -
  VQ623_RS04385 (VQ623_04385) - 882262..883167 (+) 906 WP_107611698.1 carbohydrate kinase family protein -
  VQ623_RS04390 (VQ623_04390) agrA 883345..884061 (-) 717 WP_037538035.1 quorum-sensing response regulator AgrA Regulator
  VQ623_RS04395 (VQ623_04395) agrC 884080..885363 (-) 1284 WP_053017475.1 quorum-sensing sensor histidine kinase AgrC -
  VQ623_RS04400 (VQ623_04400) agrD 885390..885530 (-) 141 WP_317955905.1 cyclic lactone autoinducer peptide AgrD -
  VQ623_RS04405 (VQ623_04405) - 885533..886099 (-) 567 WP_033079903.1 accessory gene regulator AgrB -
  VQ623_RS04410 (VQ623_04410) - 886829..887614 (-) 786 WP_326008341.1 carbon-nitrogen family hydrolase -
  VQ623_RS04415 (VQ623_04415) - 887684..888309 (-) 626 Protein_863 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27817.74 Da        Isoelectric Point: 5.2189

>NTDB_id=921457 VQ623_RS04390 WP_037538035.1 883345..884061(-) (agrA) [Staphylococcus haemolyticus strain MLK17]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=921457 VQ623_RS04390 WP_037538035.1 883345..884061(-) (agrA) [Staphylococcus haemolyticus strain MLK17]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCT
ATTGGAAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCAATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCAAGAATTATTGATTGCTTAGAAACTGCACACACTCGATTAAAATTAT
TATCTAAAGAAAGTACTGTTGAGACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGATTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAATAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTATGCTTCAGTTCGTAATGTCAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

88.235

100

0.882